Autor según el artículo: Marcé-Nogué, J; Liu, J
Departamento: Enginyeria Mecànica
Autor/es de la URV: Marcé Nogué, Jordi
Palabras clave: Zebrafish Weberian apparatus Sound conduction Ostariophysi Ossicles Ontogeny Morphology Inner-ear Human middle-ear Homology Hearing Finite element method Auditory-sensitivity Adult
Resumen: Zebrafish, an essential vertebrate model, has greatly expanded our understanding of hearing. However, one area that remains unexplored is the biomechanics of the Weberian apparatus, crucial for sound conduction and perception. Using micro-computed tomography (mu CT) bioimaging, we created three-dimensional finite element models of the zebrafish Weberian ossicles. These models ranged from the exact size to scaled isometric versions with constrained geometry (1 to 10 mm in ossicular chain length). Harmonic finite element analysis of all 11 models revealed that the resonance frequency of the zebrafish's Weberian ossicular chain is approximately 900 Hz, matching their optimal hearing range. Interestingly, resonance frequency negatively correlated with size, while the ratio of peak displacement and difference of resonance frequency between tripus and scaphium remained constant. This suggests the transmission efficiency of the ossicular chain and the homogeneity of resonance frequency at both ends of the chain are not size-dependent. We conclude that the Weberian apparatus's resonance frequency can explain zebrafish's best hearing frequency, and their biomechanical characteristics are not influenced by isometric ontogeny. As the first biomechanical modelling of atympanic ear and among the few non-human ear modelling, this study provides a methodological framework for further investigations into hearing mechanisms and the hearing evolution of vertebrates.
Áreas temáticas: Saúde coletiva Psychology Pedagogical & educational research Multidisciplinary sciences Medicina ii Matemática / probabilidade e estatística Interdisciplinary research in the social sciences Interdisciplinary research in the humanities Interdisciplinar Engenharias iii Educação física Educação Cultural studies Ciencias sociales Ciencias humanas Ciências biológicas ii Ciências biológicas i Ciências agrárias i Biotechnology Biophysics Biomedical engineering Biomaterials Bioengineering Biodiversidade Biochemistry Astronomia / física Anthropology
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: jordi.marce@urv.cat
Identificador del autor: 0000-0001-9852-7027
Fecha de alta del registro: 2024-05-23
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://royalsocietypublishing.org/doi/10.1098/rsif.2023.0553
URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Journal Of The Royal Society Interface. 21 (210): 20230553-
Referencia de l'ítem segons les normes APA: Marcé-Nogué, J; Liu, J (2024). Finite element modelling of sound transmission in the Weberian apparatus of zebrafish (Danio rerio). Journal Of The Royal Society Interface, 21(210), 20230553-. DOI: 10.1098/rsif.2023.0553
DOI del artículo: 10.1098/rsif.2023.0553
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2024
Tipo de publicación: Journal Publications
Repositori URV