Autor según el artículo: de la Vega, Rocio; Sakulsriprasert, Prasert; Miro, Jordi; Jensen, Mark P
Departamento: Psicologia
Autor/es de la URV: DE LA VEGA CARRANZA, ROCÍO / Miró Martínez, Jordi
Palabras clave: Adults Assay sensitivity Clinical trial Outcomes Pain assessment Powe Program Reliability Single Therapy Validit Validity
Resumen: Pain intensity is the most commonly used outcome domain in pain clinical trials. To minimize the chances of type II error (ie, concluding that a treatment does not have beneficial effects, when in fact it does), the measure of pain intensity used should be sensitive to changes produced by effective pain treatments. Here we sought to identify the combination of pain intensity ratings that would balance the need for reliability and validity against the need to minimize assessment burden. We conducted secondary analyses using data from a completed 4 -arm clinical trial of psychological pain treatments (N = 164 adults). Current, worst, least, and average pain intensity in the past 24 hours were assessed 4 times before and after treatment using 0 to 10 numerical rating scale -11. We created a variety of composite scores using these ratings and evaluated their reliability (Cronbach's alphas) and validity (ie, associations with a gold standard score created by averaging 16 ratings and sensitivity for detecting between -group differences in treatment efficacy). We found that for each measure, reliability increased as the number of ratings used to create the measures increased and that ratings from 3 or more days were needed to have adequately strong associations with the gold standard. Regarding sensitivity, the findings suggest that composite scores made up of ratings from 4 days are needed to maximize the chances of detecting treatment effects, especially with smaller sample sizes. In conclusion, using data from 3 or 4 days of assessment may be the best practice. Perspective: Composite scores made up of at least 3 days of pain ratings appear to be needed to maximize reliability and validity while minimizing the assessment burden.
Áreas temáticas: Anesthesiology and pain medicine Biotecnología Ciências biológicas i Ciências biológicas ii Clinical neurology Educação física Enfermagem Farmacia Interdisciplinar Linguística e literatura Medicina i Medicina ii Medicina iii Neurology Neurology (clinical) Neurosciences Odontología Psicología Saúde coletiva
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: jordi.miro@urv.cat
Identificador del autor: 0000-0002-1998-6653
Fecha de alta del registro: 2024-10-12
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://www.sciencedirect.com/science/article/pii/S152659002400350X?via%3Dihub
Referencia al articulo segun fuente origial: Journal Of Pain. 25 (7): 104474-
Referencia de l'ítem segons les normes APA: de la Vega, Rocio; Sakulsriprasert, Prasert; Miro, Jordi; Jensen, Mark P (2024). Optimizing Pain Intensity Assessment in Clinical Trials: How Many Ratings are Needed to Best Balance the Need for Validity and to Minimize Assessment Burden?. Journal Of Pain, 25(7), 104474-. DOI: 10.1016/j.jpain.2024.01.339
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI del artículo: 10.1016/j.jpain.2024.01.339
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2024
Tipo de publicación: Journal Publications