Identificador: TDX:620
Autors: Dalmau Llorca, Ma. Rosa
Resum:
AIM: Evaluate the relationship between Framingham coronary risk and body composition (percentage of body grease) measured by bioelectrical impendance.SECONDARY AIMS: Know the variables which determine an increase in coronary risk.Know the relationship between body composition (body grease percentage) and physical exercise.Know the relationship between body composition (body grease percentage) and life quality.MATERIAL AND METHODSTUDY DESIGNMulticentral transversal descriptive study to know the main variables, coronary risk, body composition (% measured by bioelectrical impendance, OMRON BF 300® ), life quality (EuroQol-5D) physical exercise (LTPA) and classical risk factors (arterial hypertension, diabetes, hypercholesterolemia, smoking) from spontaneous interviews with patients at the level of primary health attention, from June 2004 to January 2006.SUBJECTS; N: 182, n1=91 high coronary risk subjects, according to Framingham (HCR) and n2=91 low coronary risk subjects, according to Framingham (LCR). We applied the necessary subject number tables for comparison of two measures by means of the t- student-Fisher proof and to detect a difference of %GC=5% and a standard deviation 9,1with α= 0.05 and β=0.05 and we adjusted the number of subjects to count a probable loss of 20%, LCR n=90 and HCR=90, being N=180 the final number of subjects.INCLUSION CRITERIA: 34-74 year old subjects, without any previous cardiovascular illness, who are in three different health areas,EXCLUSION CRITERIAPatients who suffer from active neoplasic illness, terminal chronic illness or degenerative neurological illness, which may condition patients´ body composition. Patients with previous cardiovascular illness < 34 year old and >74 year old because it was impossible to calculate the coronary risk according to Framingham.RESULTSIn order to know the study variables, which explain the increase in coronary risk we performed a regressive logistic model. The dependent variable, coronary risk according to Framingham (high or low dichotomy variable) and as independent variables, which explain the risk increase, the percentage of body grease (stratified in two categories, normal and high)These variables, through the model, obtain a classification global percentage of 76.4 % of risk with an R2 of 42.5 %. All the variables of the model explain in a significant way the increase in coronary risk, excepting the main variable, % of stratified body grease and we may detach the waist-hip quotient *100 (waist-hip multiplied by 100, because hundredths of change in the afore quotient explain important changes in coronary risk) with OR= 1,107and IC 95% OR (1,043-1,174 ); we explain that for each hundredth of increase in the quotient the risk increases 1.107. In the same way early cardiovascular illness kinship antecedents with OR=18,343 and IC 95% OR= (4,121- 81,655) and the level of studies A (we compare subjects with no studies with subjects with secondary or university studies) result in an OR=5,413 in favour of subjects with no studies. We explain that the fact of no studies, compared with university or secondary studies, increases coronary risk in OR= 5,413 with IC 95% OR (1,512-19,380). Everyday physical exercise in each group of body grease (stratified in three categories: normal, high and very high) is superior in the stratum of high GCE with 510,95 mets.min/dia and IC 95% (366,65- 655,25) with significant differences (p=0,008) among groups and without any lineal relationship between these variables.The higher life quality the less quantity of body grease (stratified in three categories), without any differences between the body grease strata but with lineal relationship between both variables ...CONCLUSIONSBody grease, measured with bio-electric impendency, does not modify coronary risk, according to Framingham The study variables which determine coronary risk increase are: waist-hip quotient, early cardiovascular illness kinship, level of studies (no studies), sub-escapular fold. Physical exercise is greater in body grease high level group. Life quality gets worse when body grease increases.