The tissue bioavailability, biomarkers, and effects of anthocyanins on human health. Studied through systematic reviews on anthocyanin-rich foods and a nutritional pre-clinical study with anthocyanin-rich red fleshed-apples. The AppleCOR Project.

Identifier:  TDX:3241

Handle: https://hdl.handle.net/20.500.11797/TDX3241

Authors:  Sandoval Ramírez, Berner Andrée

Abstract:
periment on hypercholesterolemic rats and 6 systematic reviews from the scientific literature were conducted following the most adequate methodological proceedings between February 2018 and February 2021. Results: From various systematic reviews: 1st, ACNs can be detected in multiple target tissues with medical relevance, suggesting some health effects. 2nd, C3G is the only ACN fulfilling the criteria to be considered an adequate food-intake biomarker for berry consumption in human plasma and urine. 3rd, consuming 100-150 g/day of whole-apples improves multiple CVD risk factors and reduces the risk of CVD and CVD mortality. 4th, from the animal intervention, ACN-rich apples have an anti-inflammatory