L'efecte d'una molècula estructurada de DHA sobre la qualitat i la longevitat de Caenorhabditis elegans

Identificador:  TFG:7373

Handle: https://hdl.handle.net/20.500.11797/TFG7373

Autors:  Pérez Santamaria, Alejandra

Resum:
One of the approaches being investigated to address the problem of ageing is nutrition, specifically docosahexaenoic acid (DHA) supplementation. This nutrient may help to improve cognitive function and reduce the risk of neurodegenerative diseases. This study evaluates the effects of a structured DHA molecule in C. elegans organisms, specifically the wild-type strain and a knocked-out mutant strain for the DAF16/Forkhead O (FOXO) factor. Several phenotypic and gene expression studies are used for the study. The results show that DHA-triglyceride (TG) has beneficial effects and that the DAF16/FOXO factor may be involved in these effects.