Study of the correlation between serum antibodies against SARS-CoV-2 and quantitative viral load in a cohort of more than a thousand individuals

Identifier:  TFG:4409

Handle: https://hdl.handle.net/20.500.11797/TFG4409

Authors:  Molina Pocurull, Marc

Abstract:
COVID-19 caused by SARS-CoV-2 appears in China and rapidly expanded throughout the world collapsing health services and the world economy. Between July and October 2020, we did simultaneous serological test for antibodies against SARS-CoV-2 and a RT-PCR to 1.043 Moroccan travellers. The main objective of this study is to analyse and correlate the results of the RT-PCR and serological test (including IgM and IgG) to interpret the immune system response to the SARS-CoV-2 infection. The immune system responded to the infection producing IgM and IgG. Being the infection removed, the IgM proceeded to its degradation while the IgG stayed stable as to act as antibodies of memory.