Treballs Fi de GrauBioquímica i Biotecnologia

Deregulation of Secreted Frizzled-Related Protein 5 in Nonalcoholic Fatty Liver Disease Associated with Obesity

  • Identification data

    Identifier:  TFG:4464
    Handle: https://hdl.handle.net/20.500.11797/TFG4464
    Authors:  Portillo Carrasquer, Marta
    Abstract:
    The aim of this study is to analyse the role of SFRP5 in women with morbid obesity and NAFLD. We found that irculating SFRP5 levels increase after a caloric restriction in subjects with MO regardless of NAFLD. Moreover, hepatic SFRP5 seems to have a protective role in the first steps of NAFLD, but in an advanced stage of the disease, SFRP5 is deregulated while JNK and WNT5A are activated.

  • Others:

    Access rights: info:eu-repo/semantics/openAccess
    Education area(s): Bioquímica i Biologia Molecular
    Department: Bioquímica i Biotecnologia
    Entity: Universitat Rovira i Virgili (URV)
    Confidenciality: No
    Subject: Bioquímica i biotecnologia
    Project director: Beltrán Debón, Raúl
    Work's public defense date: 2021-06-29
    Creation date in repository: 2022-03-01
    Language: en
    Academic year: 2020-2021
    Student: Portillo Carrasquer, Marta

  • Keywords:

    inflammation
    Biochemistry and biotechnology

  • Documents:

    Memòria

  • Cerca a google

    Search to google scholar