Role of proanthocyanidins on metabolic homeostasis and hepatic oxidative stress in rats subjected to different photoperiods in an obesogenic context

Identifier:  TFG:5707

Handle: https://hdl.handle.net/20.500.11797/TFG5707

Authors:  Fort Acosta, Paula

Abstract:
Fifty-four 12-week-old male Fisher 344 rats were housed under 3 different photoperiods (L18, L12 and L6). For each photoperiod, animals were divided in animals fed with standard diet and animals received cafeteria diet for 5 weeks. Then, an oral GSPE daily dose or vehicle were administered to cafeteria groups, while standard group was given only vehicle, for 4 weeks, generating 9 final groups (n=6). Results showed that GSPE (proanthocyanidins) was able to ameliorate the effect of this diet by decreasing body weight gain at L18 and by decreasing TAG levels much more on L12 than in the other two photoperiods.