COVID-19, cytokines, and inflammation

Identifier:  TFG:5722

Handle: https://hdl.handle.net/20.500.11797/TFG5722

Authors:  Ruiz de Mendoza Araiz, Bosco

Abstract:
SARS-CoV-2 firstly appeared in 2019 in Wuhan due to an increase of unusual pneumonias for unknown causes. A lot of research has been done to understand its behavior but, after two years, there some molecular mechanisms which are still unclear such as the role of cytokines. For this reason, this review pretends to summarize the role of cytokines and its immunopathology, as well as the possible treatment to avoid the cytokines storm (CS) with interferon administration. New therapeutic strategies should be investigated for the population at risk or for those who do not respond to current treatment.