Role of gut microbiota in the pathogenesis and progression of polycystic ovary syndrome (pcos) in women. A systematic review

Identifier:  TFG:5940

Handle: https://hdl.handle.net/20.500.11797/TFG5940

Authors:  Callau Llaó, Bibiana

Abstract:
Polycystic Ovary Syndrome (PCOS) is the most prevalent endocrine-metabolic pathology in reproductive-aged women. It is a multifactorial and heterogeneous disorder, mainly characterised by ovarian hyperandrogenism and related to metabolic complications. Despite significant progress in the pathophysiology, it remains invisible. The hypothesis that gut microbiota dysbiosis is involved in the pathogenesis and development of PCOS has been postulated. The aim of this study is exploring the connection of specific molecular pathways by which gut microbes affect PCOS. In a future, novel treatments with gut microbiota as a therapeutic target could be tested in patients. Even so, more research is still needed.