Creation date in repository: 2024-07-10
Abstract: One of the approaches being investigated to address the problem of ageing is nutrition, specifically docosahexaenoic acid (DHA) supplementation. This nutrient may help to improve cognitive function and reduce the risk of neurodegenerative diseases. This study evaluates the effects of a structured DHA molecule in C. elegans organisms, specifically the wild-type strain and a knocked-out mutant strain for the DAF16/Forkhead O (FOXO) factor. Several phenotypic and gene expression studies are used for the study. The results show that DHA-triglyceride (TG) has beneficial effects and that the DAF16/FOXO factor may be involved in these effects.
Subject: Caenorhabditis elegans
Language: en
Subject areas: Bioquímica y biotecnología Biochemistry and biotechnology Bioquímica i biotecnologia
Department: Bioquímica i Biotecnologia
Student: Pérez Santamaria, Alejandra
Academic year: 2022-2023
Title in different languages: El efecto de una molécula estructurada de DHA en la calidad y longevidad de Caenorhabditis elegans L'efecte d'una molècula estructurada de DHA sobre la qualitat i la longevitat de Caenorhabditis elegans
Work's public defense date: 2023-06-22
Access rights: info:eu-repo/semantics/openAccess
Keywords: DHA, longevidad saludable, antioxidantes DHA, healthy longevity, antioxidants DHA, longevitat saludable, antioxidants
Confidenciality: Si
Title in original language: The effect of a structured molecule of DHA on the quality and longevity of Caenorhabditis elegans
Project director: Rodríguez Calvo, Ricardo
Education area(s): Bioquímica i Biologia Molecular
Entity: Universitat Rovira i Virgili (URV)