A novel electrochemical immunosensor for in situ antibody quantification

Entity: Universitat Rovira i Virgili (URV)

Confidenciality: No

Education area(s): Nanociència, Materials i Processos - Tecnologia Química de Frontera 

APS: NO

Title in different languages: A novel electrochemical immunosensor for in situ antibody quantification

Abstract: Due to COVID-19, there has been an increase in the demand of Point-of-Care (POC) devices. In this work we introduce the first steps towards development of a novel POC device – an electrochemical immunosensor – that quantify in situ immunoglobulin gamma (IgG) in biological samples. We report a simple and low-cost methodology of construction of paper support-based Platinum sensors that use potentiometry for quantification. The recognition method is Enzyme-Linked Immunosorbent Assay (ELISA), through using glucose oxidase (GOX) linked antibodies. Potentiometric measurements were given based on the mixed potential mechanism. Moreover, an explanation of the sensors analytical performance, sensitivity and selectivity is provided.

Subject: Electroquimica

Academic year: 2021-2022

Language: en

Work's public defense date: 2022-09-09

Subject areas: Biochemistry and biotechnology

Student: Oulad Ali El Hammouchi, Ahlam

Department: Química Analítica i Química Orgànica

Creation date in repository: 2022-11-24

Keywords: potentiometry, ELISA, sensors

Title in original language: A novel electrochemical immunosensor for in situ antibody quantification

Access Rights: info:eu-repo/semantics/openAccess

Project director: Blondeau, Pascal Jean Claude Leon; Andrade, Francisco Javier