Elimination of interferences in enzyme-based potentiometric sensors

Identifier:  TFM:127

Handle: https://hdl.handle.net/20.500.11797/TFM127

Authors:  Magriñà Lobato, Iván

Abstract:
An approach for the elimination of interferences in an enzyme-based potentiometric glucose biosensor based on the oxidation of the interferences by using nanostructured MnO2 is presented. Two different strategies were evaluated: i) direct addition of MnO2 to the sample followed by filtration and, ii) immobilization of MnO2 over the glucose biosensor as a pre-oxidizing layer. Both strategies have been successfully tested in real samples and these preliminary results have been validated against a commercial glucometer. Additionally, these results suggest that method for the elimination of interferences presented here could be potentially applied to other enzyme-based potentiometric sensors.