Entity: Universitat Rovira i Virgili (URV)
Confidenciality: No
Education area(s): Genètica, Física i Química Forense
Title in different languages: Short Tandem Repeats in the investigation of biological paternity. Study of a case of paternity by surrogate pregnancy
Abstract: For the study of a paternity between an alleged father and his progenitor, the paternity testing it’s a very useful tool and widely recognized. To carry out this test, some specifically regions of the genome are analysed: STRs. These sequences are formed by a consensual sequence which is being repeated X times in the chromosome that is located. Furthermore, they belong to the no-coding DNA, traduced to a protein. The number of repetitions is very variable between individuals and it’s where the importance of the differentiation of individuals is. Studying a STR system, a genetic profile of all the involved individuals is going to be obtained (usually alleged father and sons or daughters) and then include or exclude this alleged father of a biological paternity with a statistical valuation.
Subject: Bioquímica i biotecnologia
Academic year: 2017-2018
Language: Català
Work's public defense date: 2018-09-07
Subject areas: Biochemistry and biotechnology
Student: Tell Sanchez, Marta
Department: Bioquímica i Biotecnologia
Creation date in repository: 2018-09-27
TFM credits: 18
Keywords: STR, paternity test, non coding DNA, repetitive DNA, alleged pather, mutations, surrogate pregnancy
Title in original language: Short Tandem Repeats en la investigació biològica de la paternitat. Estudi d'un cas de paternitat per gestació subrogada
Project director: Raúl Beltran