Short Tandem Repeats in the investigation of biological paternity. Study of a case of paternity by surrogate pregnancy

Identifier:  TFM:324

Handle: https://hdl.handle.net/20.500.11797/TFM324

Authors:  Tell Sanchez, Marta

Abstract:
For the study of a paternity between an alleged father and his progenitor, the paternity testing it’s a very useful tool and widely recognized. To carry out this test, some specifically regions of the genome are analysed: STRs. These sequences are formed by a consensual sequence which is being repeated X times in the chromosome that is located. Furthermore, they belong to the no-coding DNA, traduced to a protein. The number of repetitions is very variable between individuals and it’s where the importance of the differentiation of individuals is. Studying a STR system, a genetic profile of all the involved individuals is going to be obtained (usually alleged father and sons or daughters) and then include or exclude this alleged father of a biological paternity with a statistical valuation.