| URV's Author/s: | Babio Sánchez, Nancy Elvira / Basora Gallisà, Josep / Becerra Tomás, Nerea / Bulló Bonet, Mònica / Cabré Vila, Juan José / Castro Salomó, Antoni / Díaz López, Andres / IBARROLA JURADO, NURIA / Martín Lujan, Francisco Manuel / ROSIQUE ESTEBAN, NÚRIA / Salas Huetos, Albert / Salas Salvadó, Jorge |
| Author, as appears in the article.: | Becerra-Tomas, Nerea; Diaz-Lopez, Andres; Rosique-Esteban, Nilria; Ros, Emilio; Buil-Cosiales, Pilar; Corella, Dolores; Estruch, Ramon; Fito, Montserrat; Serra-Majem, Lluis; Aros, Fernando; Maria Lamuela-Raventos, Rosa; Fiol, Miguel; Manuel Santos-Lozano, Jose; Diez-Espino, Javier; Portoles, Olga; Salas-Salvado, Jordi |
| Author's mail: | albert.salas@urv.cat juanjose.cabre@urv.cat nerea.becerra@urv.cat andres.diaz@urv.cat paco.martin@urv.cat monica.bullo@urv.cat josep.basora@urv.cat antoni.castro@urv.cat jordi.salas@urv.cat nancy.babio@urv.cat |
| Author identifier: | 0000-0001-5914-6862 0000-0003-1082-6861 0000-0002-4429-6507 0000-0002-7500-5629 0000-0003-0359-3588 0000-0002-0218-7046 0000-0001-5441-6333 0000-0003-2700-7459 0000-0003-3527-5277 |
| Journal publication year: | 2018-06-01 |
| Publication Type: | Journal Publications |
| ISSN: | 02615614 |
| APA: | Becerra-Tomas, Nerea; Diaz-Lopez, Andres; Rosique-Esteban, Nilria; Ros, Emilio; Buil-Cosiales, Pilar; Corella, Dolores; Estruch, Ramon; Fito, Montserr (2018). Legume consumption is inversely associated with type 2 diabetes incidence in adults: A prospective assessment from the PREDIMED study.. CLINICAL NUTRITION, 37(3), 906-913. DOI: 10.1016/j.clnu.2017.03.015 |
| Paper original source: | CLINICAL NUTRITION. 37 (3): 906-913 |
| Abstract: | Legumes, a low-energy, nutrient-dense and low glycemic index food, have shown beneficial effects on glycemic control and adiposity. As such, legumes are widely recommended in diabetic diets, even though there is little evidence that their consumption protects against type 2 diabetes. Therefore the aim of the present study was to examine the associations between consumption of total legumes and specific subtypes, and type 2 diabetes risk. We also investigated the effect of theoretically substituting legumes for other protein- or carbohydrate-rich foods.Prospective assessment of 3349 participants in the PREvención con DIeta MEDiterránea (PREDIMED) study without type 2 diabetes at baseline. Dietary information was assessed at baseline and yearly during follow-up. We used Cox regression models to estimate hazard ratios (HRs) and 95% confidence intervals (95% CIs) for type-2 diabetes incidence according to quartiles of cumulative average consumption of total legumes, lentils, chickpeas, dry beans and fresh peas.During a median follow-up of 4.3 years, 266 new cases of type 2 diabetes occurred. Individuals in the highest quartile of total legume and lentil consumption had a lower risk of diabetes than those in the lowest quartile (HR: 0.65; 95% CI: 0.43, 0.96; P-trend = 0.04; and HR: 0.67; 95% CI: 0.46-0.98; P-trend = 0.05, respectively). A borderline significant association was also observed for chickpeas consumption (HR 0.68; 95% CI: 0.46, 1.00; P-trend = 0.06). Substitutions of half a serving/day of legumes for similar servings of eggs, bread, rice or baked potato was associated with lower risk of diabetes incidence.A frequent consumption of legumes, particularly lentils, in the context of a Mediterranean diet, may provide benefits on type 2 diabetes prevention in older adults at high cardiovascular risk.The trial is registered at http://www.controlled-trials.com (ISRCTN35739639). Registration date: 5th October 2005.Copyright © 2017 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved. |
| Article's DOI: | 10.1016/j.clnu.2017.03.015 |
| Link to the original source: | https://www.clinicalnutritionjournal.com/article/S0261-5614(17)30106-1/abstract |
| Paper version: | info:eu-repo/semantics/acceptedVersion |
| licence for use: | https://creativecommons.org/licenses/by/3.0/es/ |
| Department: | Bioquímica i Biotecnologia Medicina i Cirurgia |
| Licence document URL: | https://repositori.urv.cat/ca/proteccio-de-dades/ |
| Thematic Areas: | Nutrition and dietetics Nutrition & dietetics General medicine Critical care and intensive care medicine Ciência de alimentos Biotecnología |
| Keywords: | Type-2 diabetes Type 2 diabetes Risk factors Prospective studies Proportional hazards models Predimed-study Predimed study Middle aged Male Lentils Legumes Humans Glycemic index Follow-up studies Female Fabaceae Diet, mediterranean Diet Diabetes mellitus, type 2 Blood glucose Aged Adiposity predimed-study lentils legumes |
| Entity: | Universitat Rovira i Virgili |
| Record's date: | 2026-07-11 |
| Description: | Legumes, a low-energy, nutrient-dense and low glycemic index food, have shown beneficial effects on glycemic control and adiposity. As such, legumes are widely recommended in diabetic diets, even though there is little evidence that their consumption protects against type 2 diabetes. Therefore the aim of the present study was to examine the associations between consumption of total legumes and specific subtypes, and type 2 diabetes risk. We also investigated the effect of theoretically substituting legumes for other protein- or carbohydrate-rich foods.Prospective assessment of 3349 participants in the PREvención con DIeta MEDiterránea (PREDIMED) study without type 2 diabetes at baseline. Dietary information was assessed at baseline and yearly during follow-up. We used Cox regression models to estimate hazard ratios (HRs) and 95% confidence intervals (95% CIs) for type-2 diabetes incidence according to quartiles of cumulative average consumption of total legumes, lentils, chickpeas, dry beans and fresh peas.During a median follow-up of 4.3 years, 266 new cases of type 2 diabetes occurred. Individuals in the highest quartile of total legume and lentil consumption had a lower risk of diabetes than those in the lowest quartile (HR: 0.65; 95% CI: 0.43, 0.96; P-trend = 0.04; and HR: 0.67; 95% CI: 0.46-0.98; P-trend = 0.05, respectively). A borderline significant association was also observed for chickpeas consumption (HR 0.68; 95% CI: 0.46, 1.00; P-trend = 0.06). Substitutions of half a serving/day of legumes for similar servings of eggs, bread, rice or baked potato was associated with lower risk of diabetes incidence.A frequent consumption of legumes, particularly lentils, in the context of a Mediterranean diet, may provide benefits on type 2 diabetes prevention in older adu |
| Title: | Legume consumption is inversely associated with type 2 diabetes incidence in adults: A prospective assessment from the PREDIMED study. |
| Type: | Journal Publications |
| Contributor: | Universitat Rovira i Virgili |
| Subject: | Critical Care and Intensive Care Medicine,Nutrition & Dietetics,Nutrition and Dietetics Type-2 diabetes Type 2 diabetes Risk factors Prospective studies Proportional hazards models Predimed-study Predimed study Middle aged Male Lentils Legumes Humans Glycemic index Follow-up studies Female Fabaceae Diet, mediterranean Diet Diabetes mellitus, type 2 Blood glucose Aged Adiposity predimed-study lentils legumes Nutrition and dietetics Nutrition & dietetics General medicine Critical care and intensive care medicine Ciência de alimentos Biotecnología |
| Date: | 2018-06-01 |
| Language: | en |
| Creator: | Becerra-Tomas, Nerea Diaz-Lopez, Andres Rosique-Esteban, Nilria Ros, Emilio Buil-Cosiales, Pilar Corella, Dolores Estruch, Ramon Fito, Montserrat Serra-Majem, Lluis Aros, Fernando Maria Lamuela-Raventos, Rosa Fiol, Miguel Manuel Santos-Lozano, Jose Diez-Espino, Javier Portoles, Olga Salas-Salvado, Jordi |
| Rights: | info:eu-repo/semantics/openAccess |
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