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Validation of a Deep Learning Algorithm for Diabetic Retinopathy - imarina:5938166

Autor/es de la URV:Puig Valls, Domènec Savi / Romero Aroca, Pedro / Valls Mateu, Aïda
Autor según el artículo:Romero-Aroca, P; Verges-Puig, R; de la Torre, J; Valls, A; Relaño-Barambio, N; Puig, D; Baget-Bernaldiz, M
Direcció de correo del autor:domenec.puig@urv.cat
domenec.puig@urv.cat
pedro.romero@urv.cat
pedro.romero@urv.cat
aida.valls@urv.cat
aida.valls@urv.cat
Identificador del autor:0000-0002-0562-4205
0000-0002-0562-4205
0000-0002-7061-8987
0000-0002-7061-8987
0000-0003-3616-7809
0000-0003-3616-7809
Año de publicación de la revista:2020-08-01
Tipo de publicación:Journal Publications
ISSN:15305627
Referencia de l'ítem segons les normes APA:Romero-Aroca, P; Verges-Puig, R; de la Torre, J; Valls, A; Relaño-Barambio, N; Puig, D; Baget-Bernaldiz, M (2020). Validation of a Deep Learning Algorithm for Diabetic Retinopathy. Telemedicine And E-Health, 26(8), 1001-1009. DOI: 10.1089/tmj.2019.0137
Referencia al articulo segun fuente origial:Telemedicine And E-Health. 26 (8): 1001-1009
Resumen:Background: To validate our deep learning algorithm (DLA) to read diabetic retinopathy (DR) retinographies. Introduction: Currently DR detection is made by retinography; due to its increasing diabetes mellitus incidence we need to find systems that help us to screen DR. Materials and Methods: The DLA was built and trained using 88,702 images from EyePACS, 1,748 from Messidor-2, and 19,230 from our own population. For validation a total of 38,339 retinographies from 17,669 patients (obtained from our DR screening databases) were read by a DLA and compared by four senior retina ophthalmologists for detecting any-DR and referable-DR. We determined the values of Cohen's weighted Kappa (CWK) index, sensitivity (S), specificity (SP), positive predictive value (PPV) and negative predictive value (NPV), and errors type I and II. Results: The results of the DLA to detect any-DR were: CWK = 0.886 +/- 0.004 (95% confidence interval [CI] 0.879-0.894), S = 0.967%, SP = 0.976%, PPV = 0.836%, and NPV = 0.996%. The error type I = 0.024, and the error type II = 0.004. Likewise, the referable-DR results were: CWK = 0.809 (95% CI 0.798-0.819), S = 0.998, SP = 0.968, PPV = 0.701, NPV = 0.928, error type I = 0.032, and error type II = 0.001. Discussion: Our DLA can be used as a high confidence diagnostic tool to help in DR screening, especially when it might be difficult for ophthalmologists or other professionals to identify. It can identify patients with any-DR and those that should be referred. Conclusions: The DLA can be valid to aid in screening of DR.
DOI del artículo:10.1089/tmj.2019.0137
Departamento:Enginyeria Informàtica i Matemàtiques
URL Documento de licencia:https://repositori.urv.cat/ca/proteccio-de-dades/
Áreas temáticas:Medicine (miscellaneous)
Health information management
Health informatics
Health care sciences & services
General medicine
Ciência da computação
Palabras clave:System
Sensitivity and specificity
Screening of diabetic retinopathy
Quality education
Prevalence
Ophthalmologists
Mass screening
Humans
Guidelines
Family physicians
Diagnostic techniques, ophthalmological
Diabetic retinopathy
Diabetes mellitus
Deep learning
Convolutional neural network
Algorithms
Agreement
diabetic retinopathy
deep learning
convolutional neural network
Entidad:Universitat Rovira i Virgili
Fecha de alta del registro:2026-05-09
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