Articles producció científica> Medicina i Cirurgia

Sex differences in the effect of childhood trauma on the clinical expression of early psychosis

  • Dades identificatives

    Identificador: PC:1515
    Autors:
    Alfonso Gutiérrez-ZotesMyriam GarciaItziar MontalvoMarta CreusÁngel CabezasMontse SoléMaria José AlgoraIrene MorenoJavier Labad
    Resum:
    Childhood trauma, a risk factor of psychosis, is associated the clinical expression of the illness (greater severity of psychotic symptoms; poorer cognitive performance). We aimed to explore whether there are sex differences in this relationship. We studied 79 individuals with a psychotic disorder (PD) with < 3 years of illness and 59 healthy subjects (HS). All participants were administered the MATRICS Cognitive Consensus Cognitive Battery (MCCB) to assess cognition. Depressive, positive and negative psychotic symptoms, and global functioning were also assessed. History of childhood trauma was assessed using the Childhood Trauma Questionnaire (CTQ). Patients reported a greater history of childhood trauma on all CTQ domains (emotional, physical and sexual abuse, and physical and emotional neglect). A poorer cognitive performance was also observed in PD when compared to HS. No sex differences were found in the CTQ scores. In the relationship between childhood trauma and psychopathological symptoms, significant correlations were found between CTQ scores and positive and negative psychotic symptoms, depressive symptoms and poorer functionality, but only in women. Childhood trauma was associated with poorer social cognition in both men and women. Of all CTQ dimensions, emotional neglect and physical neglect were more clearly associated with a more severe psychopathological and cognitive profile. Our results suggest that childhood trauma, particularly emotional and physical neglect, is associated with the clinical expression of psychosis and that there are sex differences in this relationship.
  • Altres:

    Autor segons l'article: Alfonso Gutiérrez-Zotes; Myriam Garcia; Itziar Montalvo; Marta Creus; Ángel Cabezas; Montse Solé; Maria José Algora; Irene Moreno; Javier Labad
    Departament: Medicina i Cirurgia
    Autor/s de la URV: GUTIÉRREZ ZOTES, JOSÉ ALFONSO; Myriam Garcia; Itziar Montalvo; Marta Creus; Ángel Cabezas; Montse Solé; Maria José Algora; Irene Moreno; Javier Labad
    Paraules clau: sex differences childhood trauma
    Resum: Childhood trauma, a risk factor of psychosis, is associated the clinical expression of the illness (greater severity of psychotic symptoms; poorer cognitive performance). We aimed to explore whether there are sex differences in this relationship. We studied 79 individuals with a psychotic disorder (PD) with < 3 years of illness and 59 healthy subjects (HS). All participants were administered the MATRICS Cognitive Consensus Cognitive Battery (MCCB) to assess cognition. Depressive, positive and negative psychotic symptoms, and global functioning were also assessed. History of childhood trauma was assessed using the Childhood Trauma Questionnaire (CTQ). Patients reported a greater history of childhood trauma on all CTQ domains (emotional, physical and sexual abuse, and physical and emotional neglect). A poorer cognitive performance was also observed in PD when compared to HS. No sex differences were found in the CTQ scores. In the relationship between childhood trauma and psychopathological symptoms, significant correlations were found between CTQ scores and positive and negative psychotic symptoms, depressive symptoms and poorer functionality, but only in women. Childhood trauma was associated with poorer social cognition in both men and women. Of all CTQ dimensions, emotional neglect and physical neglect were more clearly associated with a more severe psychopathological and cognitive profile. Our results suggest that childhood trauma, particularly emotional and physical neglect, is associated with the clinical expression of psychosis and that there are sex differences in this relationship.
    Grup de recerca: Grup d'Investigació en Psiquiatria
    Àrees temàtiques: Health sciences Ciencias de la salud Ciències de la salut
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 0010-440X
    Identificador de l'autor: N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D
    Data d'alta del registre: 2016-05-10
    Pàgina final: 96
    Volum de revista: 68
    Versió de l'article dipositat: info:eu-repo/semantics/acceptedVersion
    Enllaç font original: https://www.sciencedirect.com/science/article/abs/pii/S0010440X15302480
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    DOI de l'article: 10.1016/j.comppsych.2016.04.004
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2016
    Pàgina inicial: 86
    Tipus de publicació: Article Artículo Article
  • Paraules clau:

    Diferències entre sexes (Psicologia)
    Infants -- Psicopatologia
    Trastorns afectius en els infants
    sex differences
    childhood trauma
    Health sciences
    Ciencias de la salud
    Ciències de la salut
    0010-440X
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