The usefulness of fleet rectal enemas on high-dose-rate intracavitary cervical cancer brachytherapy. A prospective trial

Identificador:  imarina:3410328

Handle: https://hdl.handle.net/20.500.11797/imarina3410328

Autors:  Andres, Ignacio; Gutierrez-Perez, Manuel; Pilar Rodriguez-Vela, Maria; Berenguer, Roberto; Sevillano, Marimar; Aguayo, Manuel; Arenas, Meritxell; Rovirosa, Angeles; Murria-Perez, Yashmina; Sabater, Sebastia

Resum:
To evaluate the effects of rectal enemas on rectal doses during radical high-dose-rate (HDR) intracavitary cervical brachytherapy (BT).Twenty patients suffering from cervical cancer and treated with external beam radiotherapy and HDR-BT were included in a prospective trial. The first brachytherapy fraction was considered the basal status, and patients were instructed to self-administer two rectal cleansing enemas before the second fraction. Dose-volume histogram (DVH) values were generated for the rectum and correlated with rectal volume variation. Brachytherapy was carried out with a Fletcher or Utrecht applicator.No significant rectal volume differences were observed between fractions with or without rectal enemas (without, 52.64 ± 15.92 cc; with, 53.16 ± 19.28 cc). There was a significant correlation between both rectal volumes (r = 0.722, p = 0.001). No significant differences were observed in analyzed DVH parameters (median values: ?D0.1cc, 4.17 vs. 3.61 Gy; ?D1cc, 3.23 vs. 2.87 Gy; ?D2cc, 2.9 vs. 2.54 Gy; ?D5cc, 2.35 vs. 2.05 Gy, for no enema and enema fraction, respectively). No significant rectal volume differences nor DVH parameter differences were observed according the applicator type.Our rectal enemas protocol prior to HDR-BT was ineffective in significantly modifying rectal DVH parameters. No differences were observed according to the type of applicator used.