Articles producció científica> Ciències Mèdiques Bàsiques

Cladosporium species recovered from clinical samples in the United States

  • Dades identificatives

    Identificador: imarina:4123804
    Autors:
    Sandoval-Denis MSutton DMartin-Vicente ACano-Lira JWiederhold NGuarro JGené J
    Resum:
    © 2015 American Society for Microbiology. All Rights Reserved. Cladosporium species are ubiquitous, saprobic, dematiaceous fungi, only infrequently associated with human and animal opportunistic infections. We have studied a large set of Cladosporium isolates recovered from clinical samples in the United States to ascertain the predominant species there in light of recent taxonomic changes in this genus and to determine whether some could possibly be rare potential pathogens. A total of 92 isolates were identified using phenotypic and molecular methods, which included sequence analysis of the internal transcribed spacer (ITS) region and a fragment of the large subunit (LSU) of the nuclear ribosomal DNA (rDNA), as well as fragments of the translation elongation factor 1 alpha (EF-1-) and actin (Act) genes. The most frequent species was Cladosporium halotolerans (14.8%), followed by C. tenuissimum (10.2%), C. subuliforme (5.7%), and C. pseudocladosporioides (4.5%). However, 39.8% of the isolates did not correspond to any known species and were deemed to comprise at least 17 new lineages for Cladosporium. The most frequent anatomic site of isolation was the respiratory tract (54.5%), followed by superficial (28.4%) and deep tissues and fluids (14.7%). Species of the two recently described cladosporiumlike genera Toxicocladosporium and Penidiella are reported for the first time from clinical samples. In vitro susceptibility testing of 92 isolates against nine antifungal drugs showed a variety of results but high activity overall for the azoles, echinocandins, and terbinafine.
  • Altres:

    Autor segons l'article: Sandoval-Denis M; Sutton D; Martin-Vicente A; Cano-Lira J; Wiederhold N; Guarro J; Gené J
    Departament: Ciències Mèdiques Bàsiques
    Autor/s de la URV: Cano Lira, José Francisco / Gené Díaz, Josepa / Guarro Artigas, Josep / MARTÍN VICENTE, ADELA / SANDOVAL DENIS, MARCELO PATRICIO
    Paraules clau: Life on land
    Resum: © 2015 American Society for Microbiology. All Rights Reserved. Cladosporium species are ubiquitous, saprobic, dematiaceous fungi, only infrequently associated with human and animal opportunistic infections. We have studied a large set of Cladosporium isolates recovered from clinical samples in the United States to ascertain the predominant species there in light of recent taxonomic changes in this genus and to determine whether some could possibly be rare potential pathogens. A total of 92 isolates were identified using phenotypic and molecular methods, which included sequence analysis of the internal transcribed spacer (ITS) region and a fragment of the large subunit (LSU) of the nuclear ribosomal DNA (rDNA), as well as fragments of the translation elongation factor 1 alpha (EF-1-) and actin (Act) genes. The most frequent species was Cladosporium halotolerans (14.8%), followed by C. tenuissimum (10.2%), C. subuliforme (5.7%), and C. pseudocladosporioides (4.5%). However, 39.8% of the isolates did not correspond to any known species and were deemed to comprise at least 17 new lineages for Cladosporium. The most frequent anatomic site of isolation was the respiratory tract (54.5%), followed by superficial (28.4%) and deep tissues and fluids (14.7%). Species of the two recently described cladosporiumlike genera Toxicocladosporium and Penidiella are reported for the first time from clinical samples. In vitro susceptibility testing of 92 isolates against nine antifungal drugs showed a variety of results but high activity overall for the azoles, echinocandins, and terbinafine.
    Àrees temàtiques: Zootecnia / recursos pesqueiros Saúde coletiva Química Odontología Microbiology (medical) Microbiology Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Farmacia Ensino Engenharias ii Enfermagem Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciência de alimentos Ciência da computação Biotecnología Biodiversidade
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 00951137
    Adreça de correu electrònic de l'autor: josepa.gene@urv.cat jose.cano@urv.cat
    Identificador de l'autor: 0000-0001-6195-9299 0000-0003-4495-4394
    Data d'alta del registre: 2024-11-16
    Versió de l'article dipositat: info:eu-repo/semantics/acceptedVersion
    Enllaç font original: https://journals.asm.org/doi/10.1128/jcm.01482-15
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Journal Of Clinical Microbiology. 53 (9): 2990-3000
    Referència de l'ítem segons les normes APA: Sandoval-Denis M; Sutton D; Martin-Vicente A; Cano-Lira J; Wiederhold N; Guarro J; Gené J (2015). Cladosporium species recovered from clinical samples in the United States. Journal Of Clinical Microbiology, 53(9), 2990-3000. DOI: 10.1128/JCM.01482-15
    DOI de l'article: 10.1128/JCM.01482-15
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2015
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Microbiology,Microbiology (Medical)
    Life on land
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Química
    Odontología
    Microbiology (medical)
    Microbiology
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    Farmacia
    Ensino
    Engenharias ii
    Enfermagem
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciência de alimentos
    Ciência da computação
    Biotecnología
    Biodiversidade
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