Autor segons l'article: Garcia-Hermoso D, Valenzuela-Lopez N, Rivero-Menendez O, Alastruey-Izquierdo A, Guarro J, Cano-Lira JF, Stchigel AM, French Mycoses Study Group
Departament: Ciències Mèdiques Bàsiques
Autor/s de la URV: Cano Lira, José Francisco / Guarro Artigas, Josep / Stchigel Glikman, Alberto Miguel
Paraules clau: Agents Antifungal testing Coelomycetes Colletotrichum Genus Keratitis Medicopsis Mycosis Phoma Renal-transplant recipient
Resum: The coelomycetous fungi are difficult to properly identify from their phenotypic characterization and their role as etiologic agents of human infections is not clear. We studied the species distribution of these fungi among clinical isolates that had been collected and stored over a ten-year period in two European reference laboratories (France and Spain). We identified phenotypically and molecularly 97 isolates by sequencing the D1-D2 fragment of the 28S nrRNA (LSU) gene and we provided the in vitro antifungal susceptibility pattern of seven antifungals against 46 isolates. Species of the orders Pleosporales and Glomerellales were present in both collections, and Botryosphaeriales and Diaporthales only in the French one. The most prevalent species were Medicopsis romeroi, Neocucurbitaria keratinophila, Neocucurbitaria unguis-hominis and Paraconiothyrium cyclothyrioides, which had been recovered primarily from superficial tissues. The Didymellaceae was the most common family represented, with 27 isolates distributed into five genera. Most of the isolates tested were susceptible to antifungals, and only the geometric mean (GM) and minimal inhibitory concentration (MIC) values of itraconazole and caspofungin had higher values. This study provides a good picture of the great diversity of coelomycetous fungi in the European clinical context, and the basis for future studies on this interesting but neglected group of fungi.Copyright © 2019 British Mycological Society. Published by Elsevier Ltd. All rights reserved.
Àrees temàtiques: Biodiversidade Biotecnología Ciência de alimentos Ciências agrárias i Ciências ambientais Ciências biológicas i Ciências biológicas ii Ciências biológicas iii Ecology, evolution, behavior and systematics Economia Engenharias iv Farmacia Genetics Infectious diseases Interdisciplinar Medicina i Medicina ii Medicina veterinaria Mycology Plant science Química Zootecnia / recursos pesqueiros
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: albertomiguel.stchigel@urv.cat jose.cano@urv.cat josep.guarro@urv.cat
ISSN: 18786146
Identificador de l'autor: 0000-0003-3987-7996 0000-0003-4495-4394 0000-0002-7839-7568
Data d'alta del registre: 2023-05-21
Versió de l'article dipositat: info:eu-repo/semantics/submittedVersion
Enllaç font original: https://www.sciencedirect.com/science/article/abs/pii/S1878614618303751?via%3Dihub
Referència a l'article segons font original: Fungal Biology. 123 (4): 341-349
Referència de l'ítem segons les normes APA: Garcia-Hermoso D, Valenzuela-Lopez N, Rivero-Menendez O, Alastruey-Izquierdo A, Guarro J, Cano-Lira JF, Stchigel AM, French Mycoses Study Group (2019). Diversity of coelomycetous fungi in human infections: A 10-y experience of two European reference centres. Fungal Biology, 123(4), 341-349. DOI: 10.1016/j.funbio.2019.02.001
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI de l'article: 10.1016/j.funbio.2019.02.001
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2019
Tipus de publicació: Journal Publications