Articles producció científica> Bioquímica i Biotecnologia

Genetic Causes of Phenotypic Adaptation to the Second Fermentation of Sparkling Wines in Saccharomyces cerevisiae

  • Dades identificatives

    Identificador: imarina:5130784
    Autors:
    Marti-Raga, MariaPeltier, EmilienMas, AlbertBeltran, GemmaMarullo, Philippe
    Resum:
    Hybridization is known to improve complex traits due to heterosis and phenotypic robustness. However, these phenomena have been rarely explained at the molecular level. Here, the genetic determinism of Saccharomyces cerevisiae fermentation performance was investigated using a QTL mapping approach on an F1-progeny population. Three main QTL were detected, with positive alleles coming from both parental strains. The heterosis effect found in the hybrid was partially explained by three loci showing pseudooverdominance and dominance effects. The molecular dissection of those QTL revealed that the adaptation to second fermentation is related to pH, lipid, or osmotic regulation. Our results suggest that the stressful conditions of second fermentation have driven the selection of rare genetic variants adapted to maintain yeast cell homeostasis and, in particular, to low pH conditions.
  • Altres:

    Autor segons l'article: Marti-Raga, Maria; Peltier, Emilien; Mas, Albert; Beltran, Gemma; Marullo, Philippe;
    Departament: Bioquímica i Biotecnologia
    Autor/s de la URV: Beltran Casellas, Gemma / Mas Baron, Alberto
    Paraules clau: Vma13 Pma1 Pdr1 Msb2 Heterosis vma13 pma1 pdr1 msb2
    Resum: Hybridization is known to improve complex traits due to heterosis and phenotypic robustness. However, these phenomena have been rarely explained at the molecular level. Here, the genetic determinism of Saccharomyces cerevisiae fermentation performance was investigated using a QTL mapping approach on an F1-progeny population. Three main QTL were detected, with positive alleles coming from both parental strains. The heterosis effect found in the hybrid was partially explained by three loci showing pseudooverdominance and dominance effects. The molecular dissection of those QTL revealed that the adaptation to second fermentation is related to pH, lipid, or osmotic regulation. Our results suggest that the stressful conditions of second fermentation have driven the selection of rare genetic variants adapted to maintain yeast cell homeostasis and, in particular, to low pH conditions.
    Àrees temàtiques: Química Molecular biology Medicine (miscellaneous) Medicina i Interdisciplinar Genetics (clinical) Genetics & heredity Genetics Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Biotecnología Biodiversidade
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    Adreça de correu electrònic de l'autor: gemma.beltran@urv.cat albert.mas@urv.cat
    Identificador de l'autor: 0000-0002-7071-205X 0000-0002-0763-1679
    Data d'alta del registre: 2024-09-07
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://academic.oup.com/g3journal/article/7/2/399/6027637
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: G3-Genes Genomes Genetics. 7 (2): 399-412
    Referència de l'ítem segons les normes APA: Marti-Raga, Maria; Peltier, Emilien; Mas, Albert; Beltran, Gemma; Marullo, Philippe; (2017). Genetic Causes of Phenotypic Adaptation to the Second Fermentation of Sparkling Wines in Saccharomyces cerevisiae. G3-Genes Genomes Genetics, 7(2), 399-412. DOI: 10.1534/g3.116.037283
    DOI de l'article: 10.1534/g3.116.037283
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2017
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Genetics,Genetics & Heredity,Genetics (Clinical),Medicine (Miscellaneous),Molecular Biology
    Vma13
    Pma1
    Pdr1
    Msb2
    Heterosis
    vma13
    pma1
    pdr1
    msb2
    Química
    Molecular biology
    Medicine (miscellaneous)
    Medicina i
    Interdisciplinar
    Genetics (clinical)
    Genetics & heredity
    Genetics
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Biotecnología
    Biodiversidade
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