Articles producció científica> Ciències Mèdiques Bàsiques

Vaginal cuff brachytherapy in endometrial cancer - a technically easy treatment?

  • Dades identificatives

    Identificador: imarina:5132749
    Autors:
    Sabater SAndres ILopez-Honrubia VBerenguer RSevillano MJimenez-Jimenez ERovirosa AArenas M.
    Resum:
    Endometrial cancer (EC) is one of the most common gynecological cancers among women in the developed countries. Vaginal cuff is the main location of relapses after a curative surgical procedure and postoperative radiation therapy have proven to diminish it. Nevertheless, these results have not translated into better survival results. The preeminent place of vaginal cuff brachytherapy (VCB) in the postoperative treatment of high- to intermediate-risk EC was given by the PORTEC-2 trial, which demonstrated a similar reduction in relapses with VCB than with external beam radiotherapy (EBRT), but VCB induced less late toxicity. As a result of this trial, the use of VCB has increased in clinical practice at the expense of EBRT. A majority of the clinical reviews of VCB usually address the risk categories and patient selection but pay little attention to technical aspects of the VCB procedure. Our review aimed to address both aspects. First of all, we described the risk groups, which guide patient selection for VCB in clinical practice. Then, we depicted several technical aspects that might influence dose deposition and toxicity. Bladder distension and rectal distension as well as applicator position or patient position are some of those variables that we reviewed.
  • Altres:

    Autor segons l'article: Sabater S; Andres I; Lopez-Honrubia V; Berenguer R; Sevillano M; Jimenez-Jimenez E; Rovirosa A; Arenas M.
    Departament: Ciències Mèdiques Bàsiques
    Autor/s de la URV: Arenas Prat, Meritxell
    Paraules clau: Vaginal cuff brachytherapy Technique Rectum Endometrial cancer Bladder technique rectum endometrial cancer bladder
    Resum: Endometrial cancer (EC) is one of the most common gynecological cancers among women in the developed countries. Vaginal cuff is the main location of relapses after a curative surgical procedure and postoperative radiation therapy have proven to diminish it. Nevertheless, these results have not translated into better survival results. The preeminent place of vaginal cuff brachytherapy (VCB) in the postoperative treatment of high- to intermediate-risk EC was given by the PORTEC-2 trial, which demonstrated a similar reduction in relapses with VCB than with external beam radiotherapy (EBRT), but VCB induced less late toxicity. As a result of this trial, the use of VCB has increased in clinical practice at the expense of EBRT. A majority of the clinical reviews of VCB usually address the risk categories and patient selection but pay little attention to technical aspects of the VCB procedure. Our review aimed to address both aspects. First of all, we described the risk groups, which guide patient selection for VCB in clinical practice. Then, we depicted several technical aspects that might influence dose deposition and toxicity. Bladder distension and rectal distension as well as applicator position or patient position are some of those variables that we reviewed.
    Àrees temàtiques: Oncology Medicina i
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 11791322
    Adreça de correu electrònic de l'autor: meritxell.arenas@urv.cat
    Identificador de l'autor: 0000-0003-0815-2570
    Data d'alta del registre: 2024-09-07
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Cancer Management And Research. 9 351-362
    Referència de l'ítem segons les normes APA: Sabater S; Andres I; Lopez-Honrubia V; Berenguer R; Sevillano M; Jimenez-Jimenez E; Rovirosa A; Arenas M. (2017). Vaginal cuff brachytherapy in endometrial cancer - a technically easy treatment?. Cancer Management And Research, 9(), 351-362. DOI: 10.2147/CMAR.S119125
    DOI de l'article: 10.2147/CMAR.S119125
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2017
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Oncology
    Vaginal cuff brachytherapy
    Technique
    Rectum
    Endometrial cancer
    Bladder
    technique
    rectum
    endometrial cancer
    bladder
    Oncology
    Medicina i
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