Articles producció científica> Medicina i Cirurgia

Influence of sex and pregnancy on survival in patients admitted with heart failure: Data from a prospective multicenter registry

  • Dades identificatives

    Identificador: imarina:5133233
    Autors:
    Martínez-Sellés M., Díez-Villanueva P., Álvarez-Gracía J., Ferrero-Gregori A., Vives-Borrás M., Worner F., Bardají A., Delgado J., Vázquez R., González-Juanatey J., Fernández-Aviles F., Cinca J.
    Resum:
    Background Female sex is an independent predictor of better survival in patients with heart failure (HF), but the mechanism of this association is unknown. On the other hand, pregnancies have a strong influence on the cardiovascular system. Hypothesis Sex and previous gestations might have a prognostic impact on 1‐year mortality in patients admitted with HF. Methods We conducted an observational, prospective, consecutive, multicenter registry of 1831 patients (756 females [41.2%]) admitted with HF. Results Females had a more advanced age (75.2 ±11.4 vs 70.4 ±12.2 years), less ischemic heart disease (167 [25.3%] vs 446 [47.3%]), and higher left ventricular ejection fraction (52.0% ±16.6% vs 41.1% ±17.0%) than did men (all P values <0.001). During 1‐year follow‐up, 373 (20.4%) patients died (151 females and 222 males). Female sex was an independent predictor for survival (hazard ratio: 0.79, 95% confidence interval: 0.64-0.98, P = 0.03). In 504 women (65.9%), the exact number of previous pregnancies could be determined; 62 women (12.3%) had no previous pregnancies, 288 (57.1%) women had 1 or 2 pregnancies, and 154 women (30.6%) had ≥3 pregnancies. We found an association between the number of previous gestations and better survival (hazard ratio: 0.878, 95% confidence interval: 0.773-0.997, P = 0.045). Conclusions In patients admitted with HF, female sex and the number of previous pregnancies are independently associated with better 1‐year survival.
  • Altres:

    Autor segons l'article: Martínez-Sellés M., Díez-Villanueva P., Álvarez-Gracía J., Ferrero-Gregori A., Vives-Borrás M., Worner F., Bardají A., Delgado J., Vázquez R., González-Juanatey J., Fernández-Aviles F., Cinca J.
    Departament: Medicina i Cirurgia
    Autor/s de la URV: Bardají Ruiz, Alfredo
    Paraules clau: Women Systolic dysfunction Sex Prognosis Pregnancy Predictor Outcomes Mortality Metaanalysis Left-ventricular contractility Heart failure Ejection fraction Association prognosis pregnancy heart failure
    Resum: Background Female sex is an independent predictor of better survival in patients with heart failure (HF), but the mechanism of this association is unknown. On the other hand, pregnancies have a strong influence on the cardiovascular system. Hypothesis Sex and previous gestations might have a prognostic impact on 1‐year mortality in patients admitted with HF. Methods We conducted an observational, prospective, consecutive, multicenter registry of 1831 patients (756 females [41.2%]) admitted with HF. Results Females had a more advanced age (75.2 ±11.4 vs 70.4 ±12.2 years), less ischemic heart disease (167 [25.3%] vs 446 [47.3%]), and higher left ventricular ejection fraction (52.0% ±16.6% vs 41.1% ±17.0%) than did men (all P values <0.001). During 1‐year follow‐up, 373 (20.4%) patients died (151 females and 222 males). Female sex was an independent predictor for survival (hazard ratio: 0.79, 95% confidence interval: 0.64-0.98, P = 0.03). In 504 women (65.9%), the exact number of previous pregnancies could be determined; 62 women (12.3%) had no previous pregnancies, 288 (57.1%) women had 1 or 2 pregnancies, and 154 women (30.6%) had ≥3 pregnancies. We found an association between the number of previous gestations and better survival (hazard ratio: 0.878, 95% confidence interval: 0.773-0.997, P = 0.045). Conclusions In patients admitted with HF, female sex and the number of previous pregnancies are independently associated with better 1‐year survival.
    Àrees temàtiques: Saúde coletiva Nutrição Medicine (miscellaneous) Medicina ii Medicina i General medicine Farmacia Enfermagem Ciências biológicas ii Cardiology and cardiovascular medicine Cardiac & cardiovascular systems
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 01609289
    Adreça de correu electrònic de l'autor: alfredo.bardaji@urv.cat
    Identificador de l'autor: 0000-0003-1900-6974
    Data d'alta del registre: 2024-08-03
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://onlinelibrary.wiley.com/doi/full/10.1002/clc.22979
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Clinical Cardiology. 41 (7): 924-930
    Referència de l'ítem segons les normes APA: Martínez-Sellés M., Díez-Villanueva P., Álvarez-Gracía J., Ferrero-Gregori A., Vives-Borrás M., Worner F., Bardají A., Delgado J., Vázquez R., Gonzále (2018). Influence of sex and pregnancy on survival in patients admitted with heart failure: Data from a prospective multicenter registry. Clinical Cardiology, 41(7), 924-930. DOI: 10.1002/clc.22979
    DOI de l'article: 10.1002/clc.22979
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2018
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Cardiac & Cardiovascular Systems,Cardiology and Cardiovascular Medicine,Medicine (Miscellaneous)
    Women
    Systolic dysfunction
    Sex
    Prognosis
    Pregnancy
    Predictor
    Outcomes
    Mortality
    Metaanalysis
    Left-ventricular contractility
    Heart failure
    Ejection fraction
    Association
    prognosis
    pregnancy
    heart failure
    Saúde coletiva
    Nutrição
    Medicine (miscellaneous)
    Medicina ii
    Medicina i
    General medicine
    Farmacia
    Enfermagem
    Ciências biológicas ii
    Cardiology and cardiovascular medicine
    Cardiac & cardiovascular systems
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