Autor segons l'article: Cabré JJ; Mur T; Costa B; Barrio F; López-Moya C; Sagarra R; García-Barco M; Vizcaíno J; Bonaventura I; Ortiz N; Flores-Mateo G; Solà-Morales O; Catalan Diabetes Prevention Research Group
Departament: Medicina i Cirurgia
e-ISSN: 2077-0383
Autor/s de la URV: Cabre Vila, Juan Jose
Paraules clau: Sudomotor reflex Screening Primary care Neuropathy Diabetes mellitus Dermal electrochemical conductance
Resum: Diabetes mellitus (DM) is the leading cause of polyneuropathy in the Western world. Diabetic neuropathy (DNP) is the most common complication of diabetes and is of great clinical significance mainly due to the pain and the possibility of ulceration in the lower limbs. Early detection of neuropathy is essential in the medical management of this complication. Early unmyelinated C-fiber dysfunction is one of the typical findings of diabetic neuropathy and the first clinical manifestation of dysfunction indicating sudomotor eccrine gland impairment. In order to assess newly developed technology for the measurement of dermal electrochemical conductance (DEC), we analyzed the feasibility and effectiveness of DEC (quantitative expression of sudomotor reflex) as a screening test of DNP in primary health care centers. The study included 197 people (with type 2 diabetes, prediabetes and normal tolerance) who underwent all the protocol tests and electromyography (EMG). On comparing DEC with EMG as the gold standard, the area under the receiver operating characteristic (ROC) curve (AUC, area under the curve) was 0.58 in the whole sample, AUC = 0.65 in the diabetes population and AUC = 0.72 in prediabetes, being irrelevant in subjects without glucose disturbances (AUC = 0.47). Conclusions: In usual clinical practice, DEC is feasible, with moderate sensitivity but high specificity. It is also easy to use and interpret and requires little training, thereby making it a good screening test in populations with diabetes and prediabetes. It may also be useful in screening general populations at risk of neuropathy.
Àrees temàtiques: Medicine, general & internal Medicine (miscellaneous) Medicine (all)
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 20770383
Adreça de correu electrònic de l'autor: juanjose.cabre@urv.cat
Identificador de l'autor: 0000-0003-1082-6861
Data d'alta del registre: 2024-09-07
Volum de revista: 8
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://www.mdpi.com/2077-0383/8/5/598
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Journal Of Clinical Medicine. 8 (5): 598-598
Referència de l'ítem segons les normes APA: Cabré JJ; Mur T; Costa B; Barrio F; López-Moya C; Sagarra R; García-Barco M; Vizcaíno J; Bonaventura I; Ortiz N; Flores-Mateo G; Solà-Morales O; Catal (2019). Feasibility and Effectiveness of Electrochemical Dermal Conductance Measurement for the Screening of Diabetic Neuropathy in Primary Care. Journal Of Clinical Medicine, 8(5), 598-598. DOI: 10.3390/jcm8050598
DOI de l'article: 10.3390/jcm8050598
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2019
Pàgina inicial: 598
Tipus de publicació: Journal Publications