Articles producció científica> Medicina i Cirurgia

Feasibility and Effectiveness of Electrochemical Dermal Conductance Measurement for the Screening of Diabetic Neuropathy in Primary Care

  • Dades identificatives

    Identificador: imarina:5754745
    Autors:
    Cabré JJMur TCosta BBarrio FLópez-Moya CSagarra RGarcía-Barco MVizcaíno JBonaventura IOrtiz NFlores-Mateo GSolà-Morales OCatalan Diabetes Prevention Research Group
    Resum:
    Diabetes mellitus (DM) is the leading cause of polyneuropathy in the Western world. Diabetic neuropathy (DNP) is the most common complication of diabetes and is of great clinical significance mainly due to the pain and the possibility of ulceration in the lower limbs. Early detection of neuropathy is essential in the medical management of this complication. Early unmyelinated C-fiber dysfunction is one of the typical findings of diabetic neuropathy and the first clinical manifestation of dysfunction indicating sudomotor eccrine gland impairment. In order to assess newly developed technology for the measurement of dermal electrochemical conductance (DEC), we analyzed the feasibility and effectiveness of DEC (quantitative expression of sudomotor reflex) as a screening test of DNP in primary health care centers. The study included 197 people (with type 2 diabetes, prediabetes and normal tolerance) who underwent all the protocol tests and electromyography (EMG). On comparing DEC with EMG as the gold standard, the area under the receiver operating characteristic (ROC) curve (AUC, area under the curve) was 0.58 in the whole sample, AUC = 0.65 in the diabetes population and AUC = 0.72 in prediabetes, being irrelevant in subjects without glucose disturbances (AUC = 0.47). Conclusions: In usual clinical practice, DEC is feasible, with moderate sensitivity but high specificity. It is also easy to use and interpret and requires little training, thereby making it a good screening test in populations with diabetes and prediabetes. It may also be useful in screening general populations at risk of neuropathy.
  • Altres:

    Autor segons l'article: Cabré JJ; Mur T; Costa B; Barrio F; López-Moya C; Sagarra R; García-Barco M; Vizcaíno J; Bonaventura I; Ortiz N; Flores-Mateo G; Solà-Morales O; Catalan Diabetes Prevention Research Group
    Departament: Medicina i Cirurgia
    e-ISSN: 2077-0383
    Autor/s de la URV: Cabre Vila, Juan Jose
    Paraules clau: Sudomotor reflex Screening Primary care Neuropathy Diabetes mellitus Dermal electrochemical conductance
    Resum: Diabetes mellitus (DM) is the leading cause of polyneuropathy in the Western world. Diabetic neuropathy (DNP) is the most common complication of diabetes and is of great clinical significance mainly due to the pain and the possibility of ulceration in the lower limbs. Early detection of neuropathy is essential in the medical management of this complication. Early unmyelinated C-fiber dysfunction is one of the typical findings of diabetic neuropathy and the first clinical manifestation of dysfunction indicating sudomotor eccrine gland impairment. In order to assess newly developed technology for the measurement of dermal electrochemical conductance (DEC), we analyzed the feasibility and effectiveness of DEC (quantitative expression of sudomotor reflex) as a screening test of DNP in primary health care centers. The study included 197 people (with type 2 diabetes, prediabetes and normal tolerance) who underwent all the protocol tests and electromyography (EMG). On comparing DEC with EMG as the gold standard, the area under the receiver operating characteristic (ROC) curve (AUC, area under the curve) was 0.58 in the whole sample, AUC = 0.65 in the diabetes population and AUC = 0.72 in prediabetes, being irrelevant in subjects without glucose disturbances (AUC = 0.47). Conclusions: In usual clinical practice, DEC is feasible, with moderate sensitivity but high specificity. It is also easy to use and interpret and requires little training, thereby making it a good screening test in populations with diabetes and prediabetes. It may also be useful in screening general populations at risk of neuropathy.
    Àrees temàtiques: Medicine, general & internal Medicine (miscellaneous) Medicine (all)
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 20770383
    Adreça de correu electrònic de l'autor: juanjose.cabre@urv.cat
    Identificador de l'autor: 0000-0003-1082-6861
    Data d'alta del registre: 2024-09-07
    Volum de revista: 8
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://www.mdpi.com/2077-0383/8/5/598
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Journal Of Clinical Medicine. 8 (5): 598-598
    Referència de l'ítem segons les normes APA: Cabré JJ; Mur T; Costa B; Barrio F; López-Moya C; Sagarra R; García-Barco M; Vizcaíno J; Bonaventura I; Ortiz N; Flores-Mateo G; Solà-Morales O; Catal (2019). Feasibility and Effectiveness of Electrochemical Dermal Conductance Measurement for the Screening of Diabetic Neuropathy in Primary Care. Journal Of Clinical Medicine, 8(5), 598-598. DOI: 10.3390/jcm8050598
    DOI de l'article: 10.3390/jcm8050598
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2019
    Pàgina inicial: 598
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Medicine (Miscellaneous),Medicine, General & Internal
    Sudomotor reflex
    Screening
    Primary care
    Neuropathy
    Diabetes mellitus
    Dermal electrochemical conductance
    Medicine, general & internal
    Medicine (miscellaneous)
    Medicine (all)
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