Nut consumption and incidence of cardiovascular diseases and cardiovascular disease mortality: a meta-analysis of prospective cohort studies

Autor segons l'article: Becerra-Tomas, Nerea; Paz-Graniel, Indira; Kendall, Cyril W C; Kahleova, Hana; Rahelic, Dario; Sievenpiper, John L; Salas-Salvado, Jordi

Departament: Bioquímica i Biotecnologia

Autor/s de la URV: Becerra Tomás, Nerea / Paz Graniel, Indira del Socorro / Salas Salvadó, Jorge

Paraules clau: Walnuts; Trend estimation; Tree nuts; Stroke; Quality; Prospective studies; Peanuts; Peanut butter; Observational studies as topic; Nuts; Meta-analysis; Incidence; Humans; Failure; Dose-response; Dietary-protein sources; Coronary-heart-disease; Cardiovascular diseases; Cardiovascular disease; Atherosclerosis risk; Association; All-cause; tree nuts; peanuts; peanut butter; nuts; meta-analysis; cardiovascular disease

Resum: © The Author(s) 2019. Published by Oxford University Press on behalf of the International Life Sciences Institute. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. CONTEXT: Previous meta-analyses evaluating the association between nut consumption and the risk of cardiovascular disease (CVD) had substantial methodological limitations and lacked recently published large prospective studies; hence, making an updated meta-analysis highly desirable. OBJECTIVE: To update the clinical guidelines for nutrition therapy in relation to the European Association for the Study of Diabetes (EASD), a systematic review and meta-analysis of prospective studies was conducted using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to summarize the evidence of the association between total nuts, specific types of nuts, and the incidence of, and mortality from, CVD outcomes. DATA SOURCES: Relevant articles were identified by searching the PubMed and Cochrane databases. DATA EXTRACTION: Two independent researchers screened the articles to identify those that met the inclusion criteria. DATA ANALYSIS: The inverse variance method with fixed-effect or random-effects models was used to pool data across studies (expressed as risk ratio [RR] and 95% confidence interval [CI]). Heterogeneity was tested and quantified using the Cochrane Q test and I2-statistic, respectively. The GRADE system was used to assess the quality of the evidence. RESULTS: Nineteen studies were included in the analyses. The results revealed an inverse association between total nut consumption (comparing highest vs lowest categories) and CVD incidence (RR, 0.85; 95%CI, 0.800.91; I2, 0%), CVD mortality (RR, 0.77; 95%CI, 0.72-0.82; I2, 3%), coronary heart disease (CHD) incidence (RR, 0.82; 95%CI, 0.69-0.96; I2, 74%), CHD mortality (RR, 0.76; 95%CI, 0.67-0.86; I2, 46%), stroke mortality (RR, 0.83; 95%CI, 0.75-0.93; I2, 0%), and atrial fibrillation (RR, 0.85; 95%CI, 0.73-0.99; I2, 0%). No association was observed with stroke incidence and heart failure. The certainty of the evidence ranged from moderate to very low. CONCLUSIONS: This systematic review and meta-analysis revealed a beneficial role of nut consumption in reducing the incidence of, and mortality from, different CVD outcomes.

Àrees temàtiques: Saúde coletiva; Nutrition and dietetics; Nutrition & dietetics; Nutrição; Medicine (miscellaneous); Medicine (all); Medicina iii; Medicina ii; Medicina i; Interdisciplinar; General medicine; Enfermagem; Educação física; Ciências biológicas iii; Ciências biológicas ii; Biotecnología

Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 00296643

Adreça de correu electrònic de l'autor: indiradelsocorro.paz@urv.cat; nerea.becerra@urv.cat; indiradelsocorro.paz@urv.cat; jordi.salas@urv.cat

Data d'alta del registre: 2025-02-08

Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion

Enllaç font original: https://academic.oup.com/nutritionreviews/article/77/10/691/5540978?login=false

URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/

Referència a l'article segons font original: Nutrition Reviews. 77 (10): 691-709

Referència de l'ítem segons les normes APA: Becerra-Tomas, Nerea; Paz-Graniel, Indira; Kendall, Cyril W C; Kahleova, Hana; Rahelic, Dario; Sievenpiper, John L; Salas-Salvado, Jordi (2019). Nut consumption and incidence of cardiovascular diseases and cardiovascular disease mortality: a meta-analysis of prospective cohort studies. Nutrition Reviews, 77(10), 691-709. DOI: 10.1093/nutrit/nuz042

DOI de l'article: 10.1093/nutrit/nuz042

Entitat: Universitat Rovira i Virgili

Any de publicació de la revista: 2019

Tipus de publicació: Journal Publications