Articles producció científica> Medicina i Cirurgia

Prognostic implications of troponin I elevation in emergency department patients with tachyarrhythmia

  • Dades identificatives

    Identificador: imarina:5873999
    Autors:
    González-Del-Hoyo MCediel GCarrasquer ABonet GVásquez-Nuñez KBoqué CAlí SBardají A
    Resum:
    © 2019 The Authors. Clinical Cardiology published by Wiley Periodicals, Inc. Background: Tachyarrhythmias are very common in emergency medicine, and little is known about the long-term prognostic implications of troponin I levels in these patients. Hypothesis: This study aimed to investigate the correlation of cardiac troponin I (cTnI) levels and long-term prognosis in patients admitted to the emergency department (ED) with a primary diagnosis of tachyarrhythmia. Methods: A retrospective cohort study was conducted between January 2012 and December 2013, enrolling patients admitted to the ED with a primary diagnosis of tachyarrhythmia and having documented cTnI measurements. Clinical characteristics and 5-year all-cause mortality were analyzed. Results: Of a total of 222 subjects with a primary diagnosis of tachyarrhythmia, 73 patients had elevated levels of cTnI (32.9%). Patients with elevated cTnI levels were older and presented significantly more cardiovascular risk factors. At the 5-year follow-up, mortality was higher among patients with elevated cTnI levels (log-rank test P < 0.001). In the multivariable Cox regression analysis, elevated cTnI was an independent predictor of all-cause death (hazard ratio, 1.95, 95% confidence interval: 1.08-3.50, P = 0.026), in addition to age and prior heart failure. Conclusion: Patients admitted to the ED with a primary diagnosis of tachyarrhythmia and high cTnI levels have higher long-term mortality rates than patients with low cTnI levels. cTnI is thus a biomarker with predictive capacity for mortality in late follow-up, conferring utility in the risk stratification of this population.
  • Altres:

    Autor segons l'article: González-Del-Hoyo M; Cediel G; Carrasquer A; Bonet G; Vásquez-Nuñez K; Boqué C; Alí S; Bardají A
    Departament: Medicina i Cirurgia
    Autor/s de la URV: Bardají Ruiz, Alfredo / Bonet Pineda, Gil / Carrasquer Cucarella, Ana Maria
    Paraules clau: Up-regulation Troponin i Time factors Risk factors Risk assessment Retrospective studies Prognosis Predictive value of tests Paroxysmal supraventricular tachycardia Outcomes Myocardial-infarction Mortality Middle aged Management Male Humans Female Emergency service, hospital Emergency department Chest-pain Cardiac troponin Biomarkers Association Assay Arrhythmias, cardiac Arrhythmia Aged, 80 and over Aged cardiac troponin arrhythmia
    Resum: © 2019 The Authors. Clinical Cardiology published by Wiley Periodicals, Inc. Background: Tachyarrhythmias are very common in emergency medicine, and little is known about the long-term prognostic implications of troponin I levels in these patients. Hypothesis: This study aimed to investigate the correlation of cardiac troponin I (cTnI) levels and long-term prognosis in patients admitted to the emergency department (ED) with a primary diagnosis of tachyarrhythmia. Methods: A retrospective cohort study was conducted between January 2012 and December 2013, enrolling patients admitted to the ED with a primary diagnosis of tachyarrhythmia and having documented cTnI measurements. Clinical characteristics and 5-year all-cause mortality were analyzed. Results: Of a total of 222 subjects with a primary diagnosis of tachyarrhythmia, 73 patients had elevated levels of cTnI (32.9%). Patients with elevated cTnI levels were older and presented significantly more cardiovascular risk factors. At the 5-year follow-up, mortality was higher among patients with elevated cTnI levels (log-rank test P < 0.001). In the multivariable Cox regression analysis, elevated cTnI was an independent predictor of all-cause death (hazard ratio, 1.95, 95% confidence interval: 1.08-3.50, P = 0.026), in addition to age and prior heart failure. Conclusion: Patients admitted to the ED with a primary diagnosis of tachyarrhythmia and high cTnI levels have higher long-term mortality rates than patients with low cTnI levels. cTnI is thus a biomarker with predictive capacity for mortality in late follow-up, conferring utility in the risk stratification of this population.
    Àrees temàtiques: Saúde coletiva Nutrição Medicine (miscellaneous) Medicina ii Medicina i General medicine Farmacia Enfermagem Ciências biológicas ii Cardiology and cardiovascular medicine Cardiac & cardiovascular systems
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 01609289
    Adreça de correu electrònic de l'autor: gil.bonet@urv.cat anamaria.carrasquer@urv.cat anamaria.carrasquer@urv.cat alfredo.bardaji@urv.cat
    Identificador de l'autor: 0000-0003-1900-6974
    Data d'alta del registre: 2024-08-03
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://onlinelibrary.wiley.com/doi/full/10.1002/clc.23175
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Clinical Cardiology. 42 (5): 546-552
    Referència de l'ítem segons les normes APA: González-Del-Hoyo M; Cediel G; Carrasquer A; Bonet G; Vásquez-Nuñez K; Boqué C; Alí S; Bardají A (2019). Prognostic implications of troponin I elevation in emergency department patients with tachyarrhythmia. Clinical Cardiology, 42(5), 546-552. DOI: 10.1002/clc.23175
    DOI de l'article: 10.1002/clc.23175
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2019
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Cardiac & Cardiovascular Systems,Cardiology and Cardiovascular Medicine,Medicine (Miscellaneous)
    Up-regulation
    Troponin i
    Time factors
    Risk factors
    Risk assessment
    Retrospective studies
    Prognosis
    Predictive value of tests
    Paroxysmal supraventricular tachycardia
    Outcomes
    Myocardial-infarction
    Mortality
    Middle aged
    Management
    Male
    Humans
    Female
    Emergency service, hospital
    Emergency department
    Chest-pain
    Cardiac troponin
    Biomarkers
    Association
    Assay
    Arrhythmias, cardiac
    Arrhythmia
    Aged, 80 and over
    Aged
    cardiac troponin
    arrhythmia
    Saúde coletiva
    Nutrição
    Medicine (miscellaneous)
    Medicina ii
    Medicina i
    General medicine
    Farmacia
    Enfermagem
    Ciências biológicas ii
    Cardiology and cardiovascular medicine
    Cardiac & cardiovascular systems
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