Articles producció científica> Enginyeria Informàtica i Matemàtiques

Validation of a Deep Learning Algorithm for Diabetic Retinopathy

  • Dades identificatives

    Identificador: imarina:5938166
    Autors:
    Romero-Aroca, PedroVerges-Puig, Raquelde la Torre, JordiValls, AidaRelano-Barambio, NaiaraPuig, DomenecBaget-Bernaldiz, Marc
    Resum:
    Background: To validate our deep learning algorithm (DLA) to read diabetic retinopathy (DR) retinographies. Introduction: Currently DR detection is made by retinography; due to its increasing diabetes mellitus incidence we need to find systems that help us to screen DR. Materials and Methods: The DLA was built and trained using 88,702 images from EyePACS, 1,748 from Messidor-2, and 19,230 from our own population. For validation a total of 38,339 retinographies from 17,669 patients (obtained from our DR screening databases) were read by a DLA and compared by four senior retina ophthalmologists for detecting any-DR and referable-DR. We determined the values of Cohen's weighted Kappa (CWK) index, sensitivity (S), specificity (SP), positive predictive value (PPV) and negative predictive value (NPV), and errors type I and II. Results: The results of the DLA to detect any-DR were: CWK = 0.886 +/- 0.004 (95% confidence interval [CI] 0.879-0.894), S = 0.967%, SP = 0.976%, PPV = 0.836%, and NPV = 0.996%. The error type I = 0.024, and the error type II = 0.004. Likewise, the referable-DR results were: CWK = 0.809 (95% CI 0.798-0.819), S = 0.998, SP = 0.968, PPV = 0.701, NPV = 0.928, error type I = 0.032, and error type II = 0.001. Discussion: Our DLA can be used as a high confidence diagnostic tool to help in DR screening, especially when it might be difficult for ophthalmologists or other professionals to identify. It can identify patients with any-DR and those that should be referred. Conclusions: The DLA can be valid to aid in screening of DR.
  • Altres:

    Autor segons l'article: Romero-Aroca, Pedro; Verges-Puig, Raquel; de la Torre, Jordi; Valls, Aida; Relano-Barambio, Naiara; Puig, Domenec; Baget-Bernaldiz, Marc;
    Departament: Enginyeria Informàtica i Matemàtiques
    Autor/s de la URV: Puig Valls, Domènec Savi / Romero Aroca, Pedro / Valls Mateu, Aïda
    Paraules clau: System Screening of diabetic retinopathy Prevalence Guidelines Family physicians Diabetic retinopathy Deep learning Convolutional neural network Agreement diabetic retinopathy deep learning convolutional neural network
    Resum: Background: To validate our deep learning algorithm (DLA) to read diabetic retinopathy (DR) retinographies. Introduction: Currently DR detection is made by retinography; due to its increasing diabetes mellitus incidence we need to find systems that help us to screen DR. Materials and Methods: The DLA was built and trained using 88,702 images from EyePACS, 1,748 from Messidor-2, and 19,230 from our own population. For validation a total of 38,339 retinographies from 17,669 patients (obtained from our DR screening databases) were read by a DLA and compared by four senior retina ophthalmologists for detecting any-DR and referable-DR. We determined the values of Cohen's weighted Kappa (CWK) index, sensitivity (S), specificity (SP), positive predictive value (PPV) and negative predictive value (NPV), and errors type I and II. Results: The results of the DLA to detect any-DR were: CWK = 0.886 +/- 0.004 (95% confidence interval [CI] 0.879-0.894), S = 0.967%, SP = 0.976%, PPV = 0.836%, and NPV = 0.996%. The error type I = 0.024, and the error type II = 0.004. Likewise, the referable-DR results were: CWK = 0.809 (95% CI 0.798-0.819), S = 0.998, SP = 0.968, PPV = 0.701, NPV = 0.928, error type I = 0.032, and error type II = 0.001. Discussion: Our DLA can be used as a high confidence diagnostic tool to help in DR screening, especially when it might be difficult for ophthalmologists or other professionals to identify. It can identify patients with any-DR and those that should be referred. Conclusions: The DLA can be valid to aid in screening of DR.
    Àrees temàtiques: Saúde coletiva Odontología Medicine (miscellaneous) Medicina iii Medicina ii Medicina i Interdisciplinar Health information management Health informatics Health care sciences & services General medicine Engenharias iv Engenharias ii Enfermagem Educação física Ciência da computação Biotecnología Astronomia / física Arquitetura, urbanismo e design
    ISSN: 15305627
    Adreça de correu electrònic de l'autor: aida.valls@urv.cat pedro.romero@urv.cat domenec.puig@urv.cat
    Identificador de l'autor: 0000-0003-3616-7809 0000-0002-7061-8987 0000-0002-0562-4205
    Data d'alta del registre: 2023-02-18
    Referència a l'article segons font original: Telemedicine And E-Health. 26 (8): 1001-1009
    Referència de l'ítem segons les normes APA: Romero-Aroca, Pedro; Verges-Puig, Raquel; de la Torre, Jordi; Valls, Aida; Relano-Barambio, Naiara; Puig, Domenec; Baget-Bernaldiz, Marc; (2020). Validation of a Deep Learning Algorithm for Diabetic Retinopathy. Telemedicine And E-Health, 26(8), 1001-1009. DOI: 10.1089/tmj.2019.0137
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2020
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Health Care Sciences & Services,Health Informatics,Health Information Management,Medicine (Miscellaneous)
    System
    Screening of diabetic retinopathy
    Prevalence
    Guidelines
    Family physicians
    Diabetic retinopathy
    Deep learning
    Convolutional neural network
    Agreement
    diabetic retinopathy
    deep learning
    convolutional neural network
    Saúde coletiva
    Odontología
    Medicine (miscellaneous)
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    Health information management
    Health informatics
    Health care sciences & services
    General medicine
    Engenharias iv
    Engenharias ii
    Enfermagem
    Educação física
    Ciência da computação
    Biotecnología
    Astronomia / física
    Arquitetura, urbanismo e design
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