Autor segons l'article: Martínez-González MA; Fernandez-Lazaro CI; Toledo E; Díaz-López A; Corella D; Goday A; Romaguera D; Vioque J; Alonso-Gómez ÁM; Wärnberg J; Martínez JA; Serra-Majem L; Estruch R; Tinahones FJ; Lapetra J; Pintó X; Tur JA; López-Miranda J; Cano-Ibáñez N; Delgado-Rodríguez M; Matía-Martín P; Daimiel L; Sánchez VM; Vidal J; Vázquez C; Ros E; Buil-Cosiales P; Portoles O; Soria-Florido M; Konieczna J; Navarrete-Muñoz EM; Tojal-Sierra L; Fernández-García JC; Abete I; Henríquez-Sánchez P; Muñoz-Garach A; Santos-Lozano JM; Corbella E; Bibiloni MDM; Becerra-Tomás N; Barragan R; Castañer O; Fiol M; García de la Hera M; Belló-Mora MC; Gea A; Babio N; Fitó M; Ruiz-Canela M; Zazpe I; Salas-Salvadó J
Departament: Bioquímica i Biotecnologia
Autor/s de la URV: Babio Sánchez, Nancy Elvira / Becerra Tomás, Nerea / Díaz López, Andres / Salas Salvadó, Jorge
Paraules clau: Whole-grain intake Randomized controlled trials Questionnaire Predimed-plus Obesity Metabolic syndrome Metaanalysis Mediterranean diet adherence Health Glycemic index Fiber intake Fiber Coronary-heart-disease Cardiovascular disease Carbohydrate quality index Carbohydrate Association All-cause mortality predimed-plus obesity glycemic index fiber cardiovascular disease carbohydrate quality index carbohydrate
Resum: Copyright © The Author(s) 2019. BACKGROUND: Overall quality of dietary carbohydrate intake rather than total carbohydrate intake may determine the risk of cardiovascular disease (CVD). OBJECTIVE: We examined 6- and 12-mo changes in carbohydrate quality index (CQI) and concurrent changes in several CVD risk factors in a multicenter, randomized, primary-prevention trial (PREDIMED-Plus) based on an intensive weight-loss lifestyle intervention program. METHODS: Prospective analysis of 5373 overweight/obese Spanish adults (aged 55-75 y) with metabolic syndrome (MetS). Dietary intake information obtained from a validated 143-item semiquantitative food-frequency questionnaire was used to calculate 6- and 12-mo changes in CQI (categorized in quintiles), based on 4 criteria (total dietary fiber intake, glycemic index, whole grain/total grain ratio, and solid carbohydrate/total carbohydrate ratio). The outcomes were changes in intermediate markers of CVD. RESULTS: During the 12-mo follow-up, the majority of participants improved their CQI by increasing their consumption of fruits, vegetables, legumes, fish, and nuts and decreasing their consumption of refined cereals, added sugars, and sugar-sweetened beverages. After 6 mo, body weight, waist circumference (WC), systolic and diastolic blood pressure (BP), fasting blood glucose, glycated hemoglobin (HbA1c), triglyceride levels, triglycerides and glucose (TyG) index, and TyG-WC decreased across successive quintiles of improvement in the CQI. After 12 mo, improvements were additionally observed for HDL cholesterol and for the ratio of total to HDL cholesterol. Favorable improvements (expressed in common units of SD and 95% CI) for quintile 5 compared with quintile 1 of CQI change were observed for most risk factors, including TyG-WC (SD -0.20; 95% CI -0.26, -0.15), HbA1c (SD -0.16; 95% CI -0.23, -0.10), weight (SD -0.12; 95% CI -0.14, -0.09), systolic BP (SD -0.11; 95% CI -0.19, -0.02) and diastolic BP (SD -0.11; 95% CI -0.19, -0.04). CONCLUSIONS: Improvements in CQI were strongly associated with concurrent favorable CVD risk factor changes maintained over time in overweight/obese adults with MetS. This trial was registered as ISRCTN 89898870.
Àrees temàtiques: Serviço social Saúde coletiva Odontología Nutrition and dietetics Nutrition & dietetics Nutrição Medicine (miscellaneous) Medicina iii Medicina ii Medicina i General medicine Enfermagem Educação física Ciências biológicas ii Ciência de alimentos Biotecnología
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 00029165
Adreça de correu electrònic de l'autor: nerea.becerra@urv.cat andres.diaz@urv.cat nancy.babio@urv.cat jordi.salas@urv.cat
Identificador de l'autor: 0000-0002-4429-6507 0000-0002-7500-5629 0000-0003-3527-5277 0000-0003-2700-7459
Data d'alta del registre: 2023-02-18
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://academic.oup.com/ajcn/article/111/2/291/5685402?login=false
Referència a l'article segons font original: American Journal Of Clinical Nutrition. 111 (2): 291-306
Referència de l'ítem segons les normes APA: Martínez-González MA; Fernandez-Lazaro CI; Toledo E; Díaz-López A; Corella D; Goday A; Romaguera D; Vioque J; Alonso-Gómez ÁM; Wärnberg J; Martínez JA (2020). Carbohydrate quality changes and concurrent changes in cardiovascular risk factors: a longitudinal analysis in the PREDIMED-Plus randomized trial. American Journal Of Clinical Nutrition, 111(2), 291-306. DOI: 10.1093/ajcn/nqz298
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI de l'article: 10.1093/ajcn/nqz298
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2020
Tipus de publicació: Journal Publications
Repositori URV