Articles producció científica> Medicina i Cirurgia

Adequate calcium intake during long periods improves bone mineral density in healthy children. Data from the Childhood Obesity Project

  • Dades identificatives

    Identificador: imarina:6389073
  • Autors:

    Closa-Monasterolo R, Zaragoza-Jordana M, Ferré N, Luque V, Grote V, Koletzko B, Verduci E, Vecchi F, Escribano J, Childhood Obesity Project Group
  • Altres:

    Autor segons l'article: Closa-Monasterolo R, Zaragoza-Jordana M, Ferré N, Luque V, Grote V, Koletzko B, Verduci E, Vecchi F, Escribano J, Childhood Obesity Project Group
    Departament: Medicina i Cirurgia
    Autor/s de la URV: Closa Monasterolo, Ricardo / Escribano Subías, Joaquín / Ferre Pallas, Natalia / Gispert Llauradó, Mariona / Luque Moreno, Verònica / RUBIO TORRENTS, MARÍA DEL CARMEN / Zaragoza Jordana, Marta
    Paraules clau: Micronutrients Intake adequacy assessment Dietary intake assessment Childhood Calcium Bone mineral density intake adequacy assessment dietary intake assessment childhood calcium bone mineral density
    Resum: © 2017 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism Background: Bone mineralization can be influenced by genetic factors, hormonal status, nutrition, physical activity and body composition. The association of higher calcium (Ca) intake or Ca supplementation with better bone mineral density (BMD) remains controversial. Furthermore, it has been speculated that maintaining long-term adequate Ca intake rather than having a brief supplementation period is more effective. The aim of the study was to prospectively analyse the influence of adequate Ca intake on BMD at 7 years of age in European children. Methods: Data from the Childhood Obesity Project were analysed in a prospective longitudinal cohort trial. Dietary intake was recorded using 3-day food records at 4, 5 and 6 years of age. The probability of adequate intake (PA) of Ca was calculated following the American Institute of Medicine guidelines for individual assessments, with FAO, WHO and United Nations University joint expert consultation dietary recommendations. Children were categorised as having high Ca PA (PA >95%) or not (PA <95%). At 7 years, whole body (WB) and lumbar spine (LS) BMD were measured in the Spanish subsample by dual-energy x-ray absorptiometry. Internal BMD z-scores were calculated; BMD below −1 z-score were considered to indicate osteopenia, and BMD z-scores below −2, “low bone mineral density for age”. Results: BMD was measured in 179 children. Ca intake at 6 years was positively correlated with LS BMD at 7 years (R = 0.205, p = 0.030). A Ca increase of 100 mg/day explained 19.4% (p = 0.011) of the LS BMD z-score variation, modifying it by 0.089 (0.021, 0.157) units. Children with Ca PA >95% at 5 and 6 or from 4 to 6 years of age showed higher BMD z-scores at the LS and WB levels than children with Ca PA <95% (p < 0.001 and p < 0.05 for LS and WB BMD, respectively). Ca PA >95% maintained over 2 years explained 26.3% of the LS BMD z-score variation (p < 0.001), increasing it by 0.669 (0.202, 1.137). PA >95% maintained over 3 years explained 24.9% of the LS BMD z-score variation, increasing it by 0.773 (0.282, 1.264). The effects of Ca adequacy on WB BMD were similar. Children with PA >95% over 2 years had an Odds ratio of 13.84 and 12 for osteopenia at the LS and WB levels, respectively (p = 0.001). Conclusions: Long periods of adequate Ca intake in childhood increase BMD and reduce osteopenia risk. The Childhood Obesity Project clinical trial (CHOP) was registered at clinicaltrials.gov as NCT00338689.
    Àrees temàtiques: Saúde coletiva Química Odontología Nutrition and dietetics Nutrition & dietetics Nutrição Medicina iii Medicina ii Medicina i Interdisciplinar General medicine Farmacia Engenharias iv Enfermagem Educação física Critical care and intensive care medicine Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciência de alimentos Biotecnología
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 02615614
    Adreça de correu electrònic de l'autor: veronica.luque@urv.cat mariona.gispert@urv.cat mariona.gispert@urv.cat marta.zaragoza@urv.cat marta.zaragoza@urv.cat ricardo.closa@urv.cat natalia.ferre@urv.cat joaquin.escribano@urv.cat
    Identificador de l'autor: 0000-0003-2615-8175 0000-0002-9963-4163 0000-0002-2838-1525 0000-0002-5041-459X
    Data d'alta del registre: 2024-09-07
    Versió de l'article dipositat: info:eu-repo/semantics/acceptedVersion
    Enllaç font original: https://www.clinicalnutritionjournal.com/article/S0261-5614(17)30102-4/fulltext
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Clinical Nutrition. 37 (3): 890-896
    Referència de l'ítem segons les normes APA: Closa-Monasterolo R, Zaragoza-Jordana M, Ferré N, Luque V, Grote V, Koletzko B, Verduci E, Vecchi F, Escribano J, Childhood Obesity Project Group (2018). Adequate calcium intake during long periods improves bone mineral density in healthy children. Data from the Childhood Obesity Project. Clinical Nutrition, 37(3), 890-896. DOI: 10.1016/j.clnu.2017.03.011
    DOI de l'article: 10.1016/j.clnu.2017.03.011
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2018
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Critical Care and Intensive Care Medicine,Nutrition & Dietetics,Nutrition and Dietetics
    Micronutrients
    Intake adequacy assessment
    Dietary intake assessment
    Childhood
    Calcium
    Bone mineral density
    intake adequacy assessment
    dietary intake assessment
    childhood
    calcium
    bone mineral density
    Saúde coletiva
    Química
    Odontología
    Nutrition and dietetics
    Nutrition & dietetics
    Nutrição
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    General medicine
    Farmacia
    Engenharias iv
    Enfermagem
    Educação física
    Critical care and intensive care medicine
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciência de alimentos
    Biotecnología
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