Articles producció científica> Medicina i Cirurgia

Pulmonary embolism and 3-month outcomes in 4036 patients with venous thromboembolism and chronic obstructive pulmonary disease: data from the RIETE registry

  • Dades identificatives

    Identificador: imarina:6395959
    Autors:
    Bertoletti L, Quenet S, Laporte S, Sahuquillo JC, Conget F, Pedrajas JM, Martin M, Casado I, Riera-Mestre A, Monreal M, RIETE Investigators
    Resum:
    Patients with chronic obstructive pulmonary disease (COPD) have a modified clinical presentation of venous thromboembolism (VTE) but also a worse prognosis than non-COPD patients with VTE. As it may induce therapeutic modifications, we evaluated the influence of the initial VTE presentation on the 3-month outcomes in COPD patients.COPD patients included in the on-going world-wide RIETE Registry were studied. The rate of pulmonary embolism (PE), major bleeding and death during the first 3 months in COPD patients were compared according to their initial clinical presentation (acute PE or deep vein thrombosis (DVT)).Of the 4036 COPD patients included, 2452 (61%; 95% CI: 59.2-62.3) initially presented with PE. PE as the first VTE recurrence occurred in 116 patients, major bleeding in 101 patients and mortality in 443 patients (Fatal PE: first cause of death). Multivariate analysis confirmed that presenting with PE was associated with higher risk of VTE recurrence as PE (OR, 2.04; 95% CI: 1.11-3.72) and higher risk of fatal PE (OR, 7.77; 95% CI: 2.92-15.7).COPD patients presenting with PE have an increased risk for PE recurrences and fatal PE compared with those presenting with DVT alone. More efficient therapy is needed in this subtype of patients.
  • Altres:

    Autor segons l'article: Bertoletti L, Quenet S, Laporte S, Sahuquillo JC, Conget F, Pedrajas JM, Martin M, Casado I, Riera-Mestre A, Monreal M, RIETE Investigators
    Departament: Medicina i Cirurgia
    Autor/s de la URV: Porras Ledantes, Jose Antonio
    Paraules clau: Venous thromboembolism Pulmonary embolism Prognosis Deep venous thrombosis Chronic obstructive pulmonary diseases
    Resum: Patients with chronic obstructive pulmonary disease (COPD) have a modified clinical presentation of venous thromboembolism (VTE) but also a worse prognosis than non-COPD patients with VTE. As it may induce therapeutic modifications, we evaluated the influence of the initial VTE presentation on the 3-month outcomes in COPD patients.COPD patients included in the on-going world-wide RIETE Registry were studied. The rate of pulmonary embolism (PE), major bleeding and death during the first 3 months in COPD patients were compared according to their initial clinical presentation (acute PE or deep vein thrombosis (DVT)).Of the 4036 COPD patients included, 2452 (61%; 95% CI: 59.2-62.3) initially presented with PE. PE as the first VTE recurrence occurred in 116 patients, major bleeding in 101 patients and mortality in 443 patients (Fatal PE: first cause of death). Multivariate analysis confirmed that presenting with PE was associated with higher risk of VTE recurrence as PE (OR, 2.04; 95% CI: 1.11-3.72) and higher risk of fatal PE (OR, 7.77; 95% CI: 2.92-15.7).COPD patients presenting with PE have an increased risk for PE recurrences and fatal PE compared with those presenting with DVT alone. More efficient therapy is needed in this subtype of patients.
    Àrees temàtiques: Saúde coletiva Respiratory system Química Pulmonary and respiratory medicine Medicina iii Medicina ii Medicina i Interdisciplinar Farmacia Engenharias iv Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Biotecnología
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 14659921
    Adreça de correu electrònic de l'autor: joseantonio.porras@urv.cat
    Identificador de l'autor: 0000-0001-6418-1822
    Data d'alta del registre: 2023-02-26
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://respiratory-research.biomedcentral.com/articles/10.1186/1465-9921-14-75
    Referència a l'article segons font original: Respiratory Research. 14 75-75
    Referència de l'ítem segons les normes APA: Bertoletti L, Quenet S, Laporte S, Sahuquillo JC, Conget F, Pedrajas JM, Martin M, Casado I, Riera-Mestre A, Monreal M, RIETE Investigators (2013). Pulmonary embolism and 3-month outcomes in 4036 patients with venous thromboembolism and chronic obstructive pulmonary disease: data from the RIETE registry. Respiratory Research, 14(), 75-75. DOI: 10.1186/1465-9921-14-75
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    DOI de l'article: 10.1186/1465-9921-14-75
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2013
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Pulmonary and Respiratory Medicine,Respiratory System
    Venous thromboembolism
    Pulmonary embolism
    Prognosis
    Deep venous thrombosis
    Chronic obstructive pulmonary diseases
    Saúde coletiva
    Respiratory system
    Química
    Pulmonary and respiratory medicine
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    Farmacia
    Engenharias iv
    Educação física
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Biotecnología
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