Autor segons l'article: Tian X; Xu L; Liu X; Wang CC; Xie W; Jiménez-Herrera MF; Chen W
Departament: Infermeria
Autor/s de la URV: Jiménez Herrera, María Francisca
Paraules clau: Topical application Randomized-trial Radiotherapy Quality-of-life Prevention Oral mucositis Meta-analysis Management Honey Head and neck cancer Conventional fractionation Chemotherapy Carcinoma
Resum: © Annals of Palliative Medicine. Background: Oral mucositis is one of the most frequent, irreversible and distressing complications faced by head and neck cancer (HNC) patients undergoing radiotherapy. Several studies have investigated the role of honey in the prevention and alleviation of radiation-induced oral mucositis in HNC patients, however, a definitive conclusion has not yet been generated. We performed this updated systematic review and metaanalysis to determine whether honey can prevent and alleviate radiation-induced oral mucositis in HNC patients. Methods: We searched PubMed, EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL) and China National Knowledge Infrastructure (CNKI) through October 2019. We searched and selected literature, extracted data and assessed risk of bias accordingly, and then conducted statistical analyses with RevMan software version 5.3. Results: Seven trials involving 412 patients were included in the final analysis. Meta-analyses showed that honey did not decrease the incidence of radiation-induced oral mucositis [(relative risk (RR), 0.69; 95% confidence interval (CI), 0.40-1.18; P=0.18]; however, relieved the severity of oral mucositis (RR, 0.22; 95% CI, 0.13-0.38; P<0.001), maintained or increased weight (RR, 1.92; 95% CI, 1.33-2.77; P<0.001) and reduced the treatment interruption related to oral mucositis (RR, 0.13; 95% CI, 0.02-0.97; P=0.05). Qualitative analysis also revealed a decreased incidence of oral mucositis in the honey group. Conclusions: Based on limited evidence, honey may have a clinical benefit against radiation-induced oral mucositis in HNC patients. However, future trials with large-scale and rigorous methods are warranted to further establish the role of honey in the management of radiation-induced oral mucositis.
Àrees temàtiques: Surgery Cardiology and cardiovascular medicine Cardiac & cardiovascular systems
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: maria.jimenez@urv.cat
Identificador de l'autor: 0000-0003-2599-3742
Data d'alta del registre: 2023-05-13
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://apm.amegroups.com/article/view/47006/html
Referència a l'article segons font original: Annals Of Cardiothoracic Surgery. 9 (4): 1431-1441
Referència de l'ítem segons les normes APA: Tian X; Xu L; Liu X; Wang CC; Xie W; Jiménez-Herrera MF; Chen W (2020). Impact of honey on radiotherapy-induced oral mucositis in patients with head and neck cancer: A systematic review and meta-analysis. Annals Of Cardiothoracic Surgery, 9(4), 1431-1441. DOI: 10.21037/apm-20-44
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI de l'article: 10.21037/apm-20-44
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2020
Tipus de publicació: Journal Publications
Repositori URV