Articles producció científicaBioquímica i Biotecnologia

Adaptation of bacteria to glyphosate: a microevolutionary perspective of the enzyme 5-enolpyruvylshikimate-3-phosphate synthase

  • Dades identificatives

    Identificador:  imarina:9157037
    Handle: https://hdl.handle.net/20.500.11797/imarina9157037
    Autors:  Rainio, MJ; Ruuskanen, S; Helander, M; Saikkonen, K; Saloniemi, I; Puigbò, P
    Resum:
    Glyphosate is the leading herbicide worldwide, but it also affects prokaryotes because it targets the central enzyme (5-enolpyruvylshikimate-3-phosphate, EPSP) of the shikimate pathway in the synthesis of the three essential aromatic amino acids in bacteria, fungi and plants. Our results reveal that bacteria may easily become resistant to glyphosate through changes in the 5-enolpyruvylshikimate-3-phosphate synthase active site. This indicates the importance of examining how glyphosate affects microbe-mediated ecosystem functions and human microbiomes.

  • Altres:

    Autor segons l'article: Rainio, MJ; Ruuskanen, S; Helander, M; Saikkonen, K; Saloniemi, I; Puigbò, P
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/1758-2229.12931
    Departament: Bioquímica i Biotecnologia
    e-ISSN: 1758-2229
    Autor/s de la URV: Puigbò, Pere
    DOI de l'article: 10.1111/1758-2229.12931
    Resum: Glyphosate is the leading herbicide worldwide, but it also affects prokaryotes because it targets the central enzyme (5-enolpyruvylshikimate-3-phosphate, EPSP) of the shikimate pathway in the synthesis of the three essential aromatic amino acids in bacteria, fungi and plants. Our results reveal that bacteria may easily become resistant to glyphosate through changes in the 5-enolpyruvylshikimate-3-phosphate synthase active site. This indicates the importance of examining how glyphosate affects microbe-mediated ecosystem functions and human microbiomes.
    Any de publicació de la revista: 2021
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    Tipus de publicació: Journal Publication