Nut consumption and type 2 diabetes risk: a systematic review and meta-analysis of observational studies

Autor segons l'article: Becerra-Tomas, Nerea; Paz-Graniel, Indira; Hernandez-Alonso, Pablo; Jenkins, David J A; Kendall, Cyril W C; Sievenpiper, John L; Salas-Salvado, Jordi

Departament: Bioquímica i Biotecnologia

Autor/s de la URV: Becerra Tomás, Nerea / Paz Graniel, Indira del Socorro / Salas Salvadó, Jorge

Paraules clau: Adult; Adverse event; Aged; Article; Diabetes mellitus, type 2; Diet; Feeding behavior; Female; Food intake; Human; Humans; Incidence; Male; Meta analysis; Meta-analysis; Non insulin dependent diabetes mellitus; Nonhuman; Nut; Nuts; Observational study; Peanut; Peanut butter; Peanuts; Prevalence; Quantitative analysis; Risk; Systematic review; Tree nuts; Type 2 diabetes; Walnut; Walnuts

Resum: Background: Previous meta-analyses, with some methodological controversies, have assessed the relation between nut consumption and type 2 diabetes (T2D) risk and pointed to contradictory results, making desirable the performance of an updated meta-analysis. Objectives: We aimed to systematically review and meta-analyze all the published studies investigating the relations of total nuts and different types of nuts-i.e., walnuts, peanuts, peanut butter, and total tree nuts-with the prevalence and incidence of T2D. Methods: A systematic search was conducted in the PubMed and Cochrane databases through 12 August, 2020. The inverse variance method with fixed-effect models was used to pool data across studies, expressed as risk ratios (RRs) or ORs and 95% CIs for prospective cohort and cross-sectional studies, respectively. The Cochran Q test and I-2 statistics were used to test and quantify heterogeneity, respectively. Dose-response meta-analysis was also conducted. Results: Eight studies (5 prospective and 3 cross-sectional) were included in the quantitative synthesis. Meta-analyses of cross-sectional studies and prospective cohort studies, comparing the highest with the lowest categories, revealed a nonsignificant association between total nut consumption and T2D. Meta-analyses of prospective cohort studies showed an inverse association between peanut butter consumption and T2D incidence (RR: 0.87; 95% CI: 0.77, 0.98; I-2 = 50.6%; P-heterogeneity = 0.16), whereas no association was observed between peanuts or tree nuts and T2D. There was no evidence of a linear dose-response or nonlinear dose-response gradient for total nut and peanut consumption in prospective cohort studies. The certainty of the evidence using NutriGrade was very low for all the exposures. Conclusions: Current results do not demonstrate an association of total nut, peanut, or tree nut consumption with T2D. Peanut butter consumption may be inversely associated with this disease.

Àrees temàtiques: Biotecnología; Ciência de alimentos; Ciências biológicas ii; Educação física; Enfermagem; General medicine; Medicina i; Medicina ii; Medicina iii; Medicine (miscellaneous); Nutrição; Nutrition & dietetics; Nutrition and dietetics; Odontología; Saúde coletiva; Serviço social

Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/

Adreça de correu electrònic de l'autor: jordi.salas@urv.cat; indiradelsocorro.paz@urv.cat; nerea.becerra@urv.cat; indiradelsocorro.paz@urv.cat

Data d'alta del registre: 2025-02-08

Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion

Enllaç font original: https://www.sciencedirect.com/science/article/pii/S0002916522006633?via%3Dihub

Referència a l'article segons font original: American Journal Of Clinical Nutrition. 113 (4): 960-971

Referència de l'ítem segons les normes APA: Becerra-Tomas, Nerea; Paz-Graniel, Indira; Hernandez-Alonso, Pablo; Jenkins, David J A; Kendall, Cyril W C; Sievenpiper, John L; Salas-Salvado, Jordi (2021). Nut consumption and type 2 diabetes risk: a systematic review and meta-analysis of observational studies. American Journal Of Clinical Nutrition, 113(4), 960-971. DOI: 10.1093/ajcn/nqaa358

URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/

DOI de l'article: 10.1093/ajcn/nqaa358

Entitat: Universitat Rovira i Virgili

Any de publicació de la revista: 2021

Tipus de publicació: Journal Publications