Articles producció científica> Medicina i Cirurgia

Impact of comorbidities in the decision of using invasive management in elderly patients with NSTEACS

  • Dades identificatives

    Identificador: imarina:9242142
    Autors:
    Pernias VGarcia Acuna JMRaposeiras-Roubin SBarrabes JACordero AMartinez-Selles MBardaji ADiez-Villanueva PMarin FRuiz-Nodar JMVicente-Ibarra NAlonso Salinas GLRigueiro PAbu-Assi EFormiga FNunez JNunez EAriza-Sole ASanchis J
    Resum:
    Introduction and objectives: The presence of comorbidities in elderly patients with non-ST-segment elevation acute coronary syndrome worsens its prognosis. The objective of the study was to analyze the impact of the burden of comorbidities in the decision of using invasive management in these patients. Methods: A total of 7211 patients > 70 years old from 11 Spanish registries were included. Individual data were analyzed in a common database. We assessed the presence of 6 comorbidities and their association with coronary angiography during admission. Results: The mean age was 79 ± 6 years and the mean CRACE score was 150 ± 21 points. A total of 1179 patients (16%) were treated conservatively. The presence of each comorbidity was associated with less invasive management (adjusted for predictive clinical variables): Cerebrovascular disease (OR, 0.78; 95%CI, 0.64-0.95; P = .01), anemia (OR, 0.64; 95%CI, 0.54-0.76; P < .0001), chronic kidney disease (OR, 0.65; 95%CI, 0.56-0.75; P < .0001), peripheral arterial disease (OR, 0.79; 95%CI, 0.65-0.96; P = .02), chronic lung disease (OR, 0.85; IC95%, 0.71-0.99; P = .05), and diabetes mellitus (OR, 0.85; 95%CI, 0.74-0.98; P < .03). The increase in the number of comorbidities (comorbidity burden) was associated with a reduction in coronary angiographies after adjusting for the GRACE score: 1 comorbidity (OR, 0.66; 95%CI, 0.54-0.81), 2 comorbidities (OR, 0.55; 95%CI, 0.45-0.69), 3 comorbidities (OR, 0.37; 95%CI, 0.29-0.47), 4 comorbidities (OR, 0.33; 95%CI, 0.24-0.45), ? 5 comorbidities (OR, 0.21; 95%CI, 0.12-0.36); all P values < .0001 compared to 0. Conclusions: The number of coronary angiographies performed drops as the number of comorbidities increases in elderly patients with non-ST-segment elevation acute coronary syndrome. Mor
  • Altres:

    Autor segons l'article: Pernias V; Garcia Acuna JM; Raposeiras-Roubin S; Barrabes JA; Cordero A; Martinez-Selles M; Bardaji A; Diez-Villanueva P; Marin F; Ruiz-Nodar JM; Vicente-Ibarra N; Alonso Salinas GL; Rigueiro P; Abu-Assi E; Formiga F; Nunez J; Nunez E; Ariza-Sole A; Sanchis J
    Departament: Medicina i Cirurgia
    Autor/s de la URV: Bardají Ruiz, Alfredo
    Paraules clau: Elderly Coronary angiography Comorbidities Acute coronary syndrome
    Resum: Introduction and objectives: The presence of comorbidities in elderly patients with non-ST-segment elevation acute coronary syndrome worsens its prognosis. The objective of the study was to analyze the impact of the burden of comorbidities in the decision of using invasive management in these patients. Methods: A total of 7211 patients > 70 years old from 11 Spanish registries were included. Individual data were analyzed in a common database. We assessed the presence of 6 comorbidities and their association with coronary angiography during admission. Results: The mean age was 79 ± 6 years and the mean CRACE score was 150 ± 21 points. A total of 1179 patients (16%) were treated conservatively. The presence of each comorbidity was associated with less invasive management (adjusted for predictive clinical variables): Cerebrovascular disease (OR, 0.78; 95%CI, 0.64-0.95; P = .01), anemia (OR, 0.64; 95%CI, 0.54-0.76; P < .0001), chronic kidney disease (OR, 0.65; 95%CI, 0.56-0.75; P < .0001), peripheral arterial disease (OR, 0.79; 95%CI, 0.65-0.96; P = .02), chronic lung disease (OR, 0.85; IC95%, 0.71-0.99; P = .05), and diabetes mellitus (OR, 0.85; 95%CI, 0.74-0.98; P < .03). The increase in the number of comorbidities (comorbidity burden) was associated with a reduction in coronary angiographies after adjusting for the GRACE score: 1 comorbidity (OR, 0.66; 95%CI, 0.54-0.81), 2 comorbidities (OR, 0.55; 95%CI, 0.45-0.69), 3 comorbidities (OR, 0.37; 95%CI, 0.29-0.47), 4 comorbidities (OR, 0.33; 95%CI, 0.24-0.45), ? 5 comorbidities (OR, 0.21; 95%CI, 0.12-0.36); all P values < .0001 compared to 0. Conclusions: The number of coronary angiographies performed drops as the number of comorbidities increases in elderly patients with non-ST-segment elevation acute coronary syndrome. More studies are still needed to know what the best management of these patients should be. © 2019 Permanyer Publications. All rights reserved.
    Àrees temàtiques: Cardiology and cardiovascular medicine Cardiac & cardiovascular systems
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 2604-7322
    Adreça de correu electrònic de l'autor: alfredo.bardaji@urv.cat
    Identificador de l'autor: 0000-0003-1900-6974
    Data d'alta del registre: 2024-07-27
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://recintervcardiol.org/en/ischemic-heart-disease/impact-of-comorbidities-in-the-decision-of-using-invasive-management-in-elderly-patients-with-nsteacs
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Rec Interventional Cardiology. 3 (1): 15-20
    Referència de l'ítem segons les normes APA: Pernias V; Garcia Acuna JM; Raposeiras-Roubin S; Barrabes JA; Cordero A; Martinez-Selles M; Bardaji A; Diez-Villanueva P; Marin F; Ruiz-Nodar JM; Vice (2021). Impact of comorbidities in the decision of using invasive management in elderly patients with NSTEACS. Rec Interventional Cardiology, 3(1), 15-20. DOI: 10.24875/RECICE.M20000147
    DOI de l'article: 10.24875/RECICE.M20000147
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2021
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Cardiac & Cardiovascular Systems,Cardiology and Cardiovascular Medicine
    Elderly
    Coronary angiography
    Comorbidities
    Acute coronary syndrome
    Cardiology and cardiovascular medicine
    Cardiac & cardiovascular systems
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