Articles producció científica> Química Analítica i Química Orgànica

Ion-selective organic electrochemical transistors for the determination of potassium in clinical samples

  • Dades identificatives

    Identificador: imarina:9332544
    Autors:
    Estivill, MCYazza, AABlondeau, PAndrade, FJ
    Resum:
    The development and optimization of a paper-based ion-selective organic electrochemical transistor (IS-OECT) with an outstanding analytical performance is presented. The combination of thick-film transistor technology with a suitable optimization of the ion-selective membrane composition and thickness allows reaching sensitivities of up to 2.50 mA/decade, which is more than one order of magnitude higher than other similar devices reported up to date. The system shows good selectivity, allowing the detection of low concentrations of potassium in high saline concentrations, and a linear range from 0.1 mM to 100 mM, which covers the relevant clinical range of K+ in blood. A calibration curve for K+ in artificial serum between 1 and 10 mM shows changes in concentrations down to 0.05 mM can be discriminated. Furthermore, the device can be made with a simple manufacturing process, such as drop casting, on low-cost substrate materials and can be operated with a gate voltage of 0 V. This IS-OCET offers promising avenues for developing ion-sensing platforms for the point of need.
  • Altres:

    Autor segons l'article: Estivill, MC; Yazza, AA; Blondeau, P; Andrade, FJ
    Departament: Química Analítica i Química Orgànica
    Autor/s de la URV: Andrade, Francisco Javier / Blondeau, Pascal Jean Claude Leon
    Paraules clau: Potassium Pedot:pss Paper-based sensors Organic electrochemical transistors Ion detection Field-effect transistor potassium pedot:pss paper-based sensors organic electrochemical transistors electrodes array
    Resum: The development and optimization of a paper-based ion-selective organic electrochemical transistor (IS-OECT) with an outstanding analytical performance is presented. The combination of thick-film transistor technology with a suitable optimization of the ion-selective membrane composition and thickness allows reaching sensitivities of up to 2.50 mA/decade, which is more than one order of magnitude higher than other similar devices reported up to date. The system shows good selectivity, allowing the detection of low concentrations of potassium in high saline concentrations, and a linear range from 0.1 mM to 100 mM, which covers the relevant clinical range of K+ in blood. A calibration curve for K+ in artificial serum between 1 and 10 mM shows changes in concentrations down to 0.05 mM can be discriminated. Furthermore, the device can be made with a simple manufacturing process, such as drop casting, on low-cost substrate materials and can be operated with a gate voltage of 0 V. This IS-OCET offers promising avenues for developing ion-sensing platforms for the point of need.
    Àrees temàtiques: Surfaces, coatings and films Química Odontología Nutrição Metals and alloys Medicina ii Medicina i Materials chemistry Materiais Interdisciplinar Instruments & instrumentation Instrumentation Farmacia Engenharias iv Engenharias iii Engenharias ii Engenharias i Electronic, optical and magnetic materials Electrochemistry Electrical and electronic engineering Educação física Educação Economia Condensed matter physics Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Chemistry, analytical Biotecnología Biodiversidade Astronomia / física
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    Adreça de correu electrònic de l'autor: pascal.blondeau@urv.cat franciscojavier.andrade@urv.cat
    Identificador de l'autor: 0000-0003-1331-5055 0000-0003-1199-2837
    Data d'alta del registre: 2024-02-17
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://www.sciencedirect.com/science/article/pii/S0925400523017458
    Referència a l'article segons font original: Sensors And Actuators B-Chemical. 401
    Referència de l'ítem segons les normes APA: Estivill, MC; Yazza, AA; Blondeau, P; Andrade, FJ (2024). Ion-selective organic electrochemical transistors for the determination of potassium in clinical samples. Sensors And Actuators B-Chemical, 401(), -. DOI: 10.1016/j.snb.2023.135027
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    DOI de l'article: 10.1016/j.snb.2023.135027
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2024
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Chemistry, Analytical,Condensed Matter Physics,Electrical and Electronic Engineering,Electrochemistry,Electronic, Optical and Magnetic Materials,Instrumentation,Instruments & Instrumentation,Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films
    Potassium
    Pedot:pss
    Paper-based sensors
    Organic electrochemical transistors
    Ion detection
    Field-effect transistor
    potassium
    pedot:pss
    paper-based sensors
    organic electrochemical transistors
    electrodes
    array
    Surfaces, coatings and films
    Química
    Odontología
    Nutrição
    Metals and alloys
    Medicina ii
    Medicina i
    Materials chemistry
    Materiais
    Interdisciplinar
    Instruments & instrumentation
    Instrumentation
    Farmacia
    Engenharias iv
    Engenharias iii
    Engenharias ii
    Engenharias i
    Electronic, optical and magnetic materials
    Electrochemistry
    Electrical and electronic engineering
    Educação física
    Educação
    Economia
    Condensed matter physics
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência de alimentos
    Ciência da computação
    Chemistry, analytical
    Biotecnología
    Biodiversidade
    Astronomia / física
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