Autor segons l'article: Shyam, S; García-Gavilán, JF; Paz-Graniel, I; Gaforio, JJ; Martínez-González, MA; Corella, D; Martínez, JA; Alonso-Gómez, AM; Warnberg, J; Vioque, J; Romaguera, D; López-Miranda, J; Estruch, R; Tinahones, FJ; Lapetra, J; Serra-Majem, JL; Bueno-Cavanillas, A; Tur, JA; Sanchez, VM; Pinto, X; Matía-Martín, P; Vidal, J; Alcarria, MD; Daimiel, L; Ros, E; Fernandez-Aranda, F; Nishi, SK; Garcia-Regata, O; Araluce, RP; Asensio, EM; Castaner, O; Garcia-Rios, A; Oncina-Canovas, A; Bouzas, C; Zulet, MA; Rayo, E; Casas, R; Martin-Pelaez, S; Tojal-Sierra, L; Bernal-Lopez, MR; Carlos, S; Sorli, JV; Goday, A; Pena-Orihuela, PJ; Pastor-Morel, A; Eguaras, S; Zomeno, MD; Delgado-Rodriguez, M; Babio, N; Fito, M; Salas-Salvado, J
Departament: Bioquímica i Biotecnologia
Autor/s de la URV: Babio Sánchez, Nancy Elvira / García Gavilán, Jesús Francisco / Paz Graniel, Indira del Socorro / Salas Salvadó, Jorge / Shyam, Sangeetha
Paraules clau: mediterranean diet older adults predimed-plus sars-cov2 Covid-19 Mediterranean diet Older adults Predimed-plus Sars-cov2
Resum: Objectives: We tested the effects of a weight-loss intervention encouraging energy-reduced MedDiet and physical activity (PA) in comparison to ad libitum MedDiet on COVID-19 incidence in older adults. Design: Secondary analysis of PREDIMED-Plus, a prospective, ongoing, multicentre randomized controlled trial. Setting: Community-dwelling, free-living participants in PREDIMED-Plus trial. Participants: 6,874 Spanish older adults (55–75 years, 49% women) with overweight/obesity and metabolic syndrome. Intervention: Participants were randomised to Intervention (IG) or Control (CG) Group. IG received intensive behavioural intervention for weight loss with an energy-reduced MedDiet intervention and PA promotion. CG was encouraged to consume ad libitum MedDiet without PA recommendations. Measurements: COVID-19 was ascertained by an independent Event Committee until December 31, 2021. COX regression models compared the effect of PREDIMED-Plus interventions on COVID-19 risk. Results: Overall, 653 COVID-19 incident cases were documented (IG:317; CG:336) over a median (IQR) follow-up of 5.8 (1.3) years (inclusive of 4.0 (1.2) years before community transmission of COVID-19) in both groups. A significantly lowered risk of COVID-19 incidence was not evident in IG, compared to CG (fully-adjusted HR (95% CI): 0.96 (0.81,1.12)). Conclusions: There was no evidence to show that an intensive weight-loss intervention encouraging energy-reduced MedDiet and PA significantly lowered COVID-19 risk in older adults with overweight/ obesity and metabolic syndrome in comparison to ad libitum MedDiet. Recommendations to improve adherence to MedDiet provided with or without lifestyle modification suggestions for weight loss may have similar effects in protecting against COVID-19 risk in older adults with high cardiovascular risks.
Àrees temàtiques: Ciência de alimentos Ciências agrárias i Ciências biológicas i Ciências biológicas ii Educação Educação física Enfermagem Engenharias iii General medicine Geriatrics & gerontology Geriatrics and gerontology Interdisciplinar Medicina i Medicina ii Medicina iii Medicine (miscellaneous) Nutrição Nutrition & dietetics Nutrition and dietetics Odontología Planejamento urbano e regional / demografia Saúde coletiva Zootecnia / recursos pesqueiros
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: jesusfrancisco.garcia@urv.cat indiradelsocorro.paz@urv.cat indiradelsocorro.paz@urv.cat jordi.salas@urv.cat nancy.babio@urv.cat jesusfrancisco.garcia@urv.cat sangeetha.shyam@urv.cat
Identificador de l'autor: 0000-0002-3204-6877 0000-0002-3204-6877 0000-0003-2700-7459 0000-0003-3527-5277
Data d'alta del registre: 2024-01-29
Versió de l'article dipositat: info:eu-repo/semantics/submittedVersion
Referència a l'article segons font original: Journal Of Nutrition Health & Aging.
Referència de l'ítem segons les normes APA: Shyam, S; García-Gavilán, JF; Paz-Graniel, I; Gaforio, JJ; Martínez-González, MA; Corella, D; Martínez, JA; Alonso-Gómez, AM; Warnberg, J; Vioque, J; (2023). Intensive Weight-Loss Lifestyle Intervention Using Mediterranean Diet and COVID-19 Risk in Older Adults: Secondary Analysis of PREDIMED-Plus Trial. Journal Of Nutrition Health & Aging, (), -. DOI: 10.1007/s12603-023-2044-4
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2023
Tipus de publicació: Journal Publications
Repositori URV