Articles producció científicaCiències Mèdiques Bàsiques

Non-Invasive Matrices for the Human Biomonitoring of PFAS: An Updated Review of the Scientific Literature

  • Dades identificatives

    Identificador:  imarina:9448923
    Autors:  Nadal, Marti; Domingo, Jose L
    Resum:
    Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals widely used in consumer and industrial products due to their unique physicochemical properties. However, their persistence and bioaccumulative potential pose significant environmental and human health risks. This review focuses on the use of non-invasive matrices-urine, hair, and nails-for the human biomonitoring of PFAS, highlighting key findings from scientific studies. While urine offers a non-invasive and practical option, its limited sensitivity for long-chain PFAS requires further analytical advances. Hair and nails have demonstrated potential for use in biomonitoring, with higher detection frequencies and concentrations for certain PFAS compared to urine. The variability in PFAS levels across studies reflects differences in population characteristics, exposure sources, and geographic regions. This review emphasizes the need for standardized analytical methods, expanded population studies, and the use of complementary matrices to enhance the accuracy and reliability of PFAS exposure assessment.
  • Altres:

    Autor segons l'article: Nadal, Marti; Domingo, Jose L
    Departament: Ciències Mèdiques Bàsiques
    Autor/s de la URV: Domingo Roig, José Luis / Nadal Lomas, Martí
    Paraules clau: Urine samples; Urine; Serum; Saliv; Polyfluoroalkyl substances; Perfluorinated compounds; Per- and polyfluoroalkyl substances (pfas); Of-the-art; Nails; Nail; Human hair; Human exposure; Human biomonitoring; Hair; Environmental exposure; Environmental exposur; Blood
    Resum: Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals widely used in consumer and industrial products due to their unique physicochemical properties. However, their persistence and bioaccumulative potential pose significant environmental and human health risks. This review focuses on the use of non-invasive matrices-urine, hair, and nails-for the human biomonitoring of PFAS, highlighting key findings from scientific studies. While urine offers a non-invasive and practical option, its limited sensitivity for long-chain PFAS requires further analytical advances. Hair and nails have demonstrated potential for use in biomonitoring, with higher detection frequencies and concentrations for certain PFAS compared to urine. The variability in PFAS levels across studies reflects differences in population characteristics, exposure sources, and geographic regions. This review emphasizes the need for standardized analytical methods, expanded population studies, and the use of complementary matrices to enhance the accuracy and reliability of PFAS exposure assessment.
    Àrees temàtiques: Toxicology; Health, toxicology and mutagenesis; Environmental sciences; Chemical health and safety
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    Adreça de correu electrònic de l'autor: joseluis.domingo@urv.cat; marti.nadal@urv.cat
    Data d'alta del registre: 2025-03-15
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://www.mdpi.com/2305-6304/13/2/134
    Referència a l'article segons font original: Toxics. 13 (2): 134-
    Referència de l'ítem segons les normes APA: Nadal, Marti; Domingo, Jose L (2025). Non-Invasive Matrices for the Human Biomonitoring of PFAS: An Updated Review of the Scientific Literature. Toxics, 13(2), 134-. DOI: 10.3390/toxics13020134
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    DOI de l'article: 10.3390/toxics13020134
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2025
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Chemical Health and Safety,Environmental Sciences,Health, Toxicology and Mutagenesis,Toxicology
    Urine samples
    Urine
    Serum
    Saliv
    Polyfluoroalkyl substances
    Perfluorinated compounds
    Per- and polyfluoroalkyl substances (pfas)
    Of-the-art
    Nails
    Nail
    Human hair
    Human exposure
    Human biomonitoring
    Hair
    Environmental exposure
    Environmental exposur
    Blood
    Toxicology
    Health, toxicology and mutagenesis
    Environmental sciences
    Chemical health and safety
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