Autor segons l'article: Mostafa, Hamza; Mateu-Fabregat, Javier; Benchohra, Asmae; Novau-Ferre, Nil; Panisello, Laura; Bullo, Monica
Departament: Bioquímica i Biotecnologia
e-ISSN: 2072-6643
Autor/s de la URV: Bulló Bonet, Mònica
Paraules clau: Adolescent; Adult; Diet; Flavonoids; Humans; Infertility, male; Male; Male infertility; Nutrition; Polyphenol; Polyphenols; Semen analysis; Semen quality; Sperm motility; Spermatozoa; Young adult
Resum: Background/Objectives: Low semen quality and male infertility are critical global health issues. Emerging research highlights that nutritional factors could play a significant role in determining reproductive outcomes. Understanding and optimizing these dietary influences, including the role of polyphenols, is crucial for developing targeted strategies to improve male fertility. We aimed to explore the relationship between the intake of different classes of polyphenols and semen quality indicators in a cohort of healthy young males. Methods: This is a secondary analysis involving 106 male individuals, aged 18-35 years, from the FERTINUTS trial. Dietary intake was assessed using 3-day dietary records, and semen quality parameters were analyzed. Multivariable linear regression analysis was employed to evaluate the associations between dietary polyphenol consumption and semen quality indicators. Results: Our findings revealed both positive and negative associations between polyphenol consumption and sperm morphology parameters. A higher intake of total polyphenols was associated with a lower percentage of abnormalities in sperm heads but a higher rate of abnormalities in the principal piece. Similar results were observed for lignan and flavonoid intake. Additionally, a higher intake of flavonoids was also associated with a greater percentage of normal sperm forms. In contrast, a higher dietary intake of stilbenes was associated with a higher percentage of combined abnormalities. Conclusions: Higher intake of polyphenols, particularly flavonoids and lignans, was associated with improved sperm head morphology but also with increased tail abnormalities, although no associations with motility or vitality were observed. These results suggest that specific polyphenol classes may have both beneficial and adverse effects on sperm structure, warranting consideration of compound type and dosage in dietary recommendations. Further studies are needed to determine whether these morphological changes impact fertilization outcomes and reproductive potential.
Grup de recerca: Nutrició i Salut Metabòlica (NuMeH)
Àrees temàtiques: Biotecnología; Ciência de alimentos; Ciências agrárias i; Ciências biológicas i; Ciências biológicas ii; Ciências biológicas iii; Economia; Educação física; Enfermagem; Engenharias ii; Engenharias iv; Farmacia; Food science; Interdisciplinar; Medicina i; Medicina ii; Medicina iii; Medicina veterinaria; Nutrição; Nutrition & dietetics; Nutrition and dietetics; Planejamento urbano e regional / demografia; Psicología; Química; Saúde coletiva; Zootecnia / recursos pesqueiros
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: monica.bullo@urv.cat
Data d'alta del registre: 2025-09-27
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://www.mdpi.com/journal/nutrients
Referència a l'article segons font original: Nutrients. 17 (17): 2785-
Referència de l'ítem segons les normes APA: Mostafa, Hamza; Mateu-Fabregat, Javier; Benchohra, Asmae; Novau-Ferre, Nil; Panisello, Laura; Bullo, Monica (2025). Association Between Dietary Polyphenol Intake and Semen Quality: Insights from the FERTINUTS Study. Nutrients, 17(17), 2785-. DOI: 10.3390/nu17172785
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI de l'article: 10.3390/nu17172785
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2025
Tipus de publicació: Journal Publications
Repositori URV