Articles producció científica> Química Analítica i Química Orgànica

Topological Defects in Hyperbranched Glycopolymers Enhance Binding to Lectins

  • Identification data

    Identifier: PC:3074
    Authors:
    Castillón, S.Salvadó, M.Reina, J.Rojo, J.Boutureira, O.
    Abstract:
    Central scaffold topology and carbohydrate density are important features in determining both the binding mechanism and potency of synthetic multivalent, polydisperse vs. monodisperse carbohydrate systems to a model plant toxin (RCA120). We found lower densities of protein receptors favour the use of heterogeneous, polydisperse glycoconjugate presentations as determined by surface plasmon resonance (SPR) and dynamic light scattering (DLS).
  • Others:

    Author, as appears in the article.: Castillón, S. ; Salvadó, M. ; Reina, J.; Rojo, J. ; Boutureira, O.
    Department: Química Analítica i Química Orgànica
    URV's Author/s: CASTILLÓN MIRANDA, SERGIO; Salvadó, M. ; Reina, J.; Rojo, J. ; Boutureira, O.
    Keywords: molecular recognition dendrimers carbohydrates
    Abstract: Central scaffold topology and carbohydrate density are important features in determining both the binding mechanism and potency of synthetic multivalent, polydisperse vs. monodisperse carbohydrate systems to a model plant toxin (RCA120). We found lower densities of protein receptors favour the use of heterogeneous, polydisperse glycoconjugate presentations as determined by surface plasmon resonance (SPR) and dynamic light scattering (DLS).
    Research group: Síntesis Orgànica Estereoselectiva
    Thematic Areas: Chemistry Química Química
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 1521-3765
    Author identifier: 0000-0002-0690-7549; ; ; ;
    Record's date: 2018-02-23
    Last page: 15790
    Journal volume: 23
    Papper version: info:eu-repo/semantics/acceptedVersion
    Link to the original source: http://onlinelibrary.wiley.com/doi/10.1002/chem.201703432/full
    Funding program: plan; RYC- 2015-17705 plan; Excelencia; CTQ2014-52328-P plan; Excelencia; CTQ2014-58664-R
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.1002/chem.201703432
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2017
    First page: 15790
    Publication Type: Article Artículo Article
  • Keywords:

    Reconeixement molecular
    Dendrímers
    Hidrats de carboni
    molecular recognition
    dendrimers
    carbohydrates
    Chemistry
    Química
    Química
    1521-3765
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