Author, as appears in the article.: Sandoval-Ramírez, Berner Andrée; Catalán, Úrsula; Fernández-Castillejo, Sara; Rubió, Laura; Macià, Alba; Solà, Rosa
Department: Medicina i Cirurgia
URV's Author/s: SANDOVAL RAMÍREZ, BERNER ANDRÉE; CATALÁN SANTOS, ÚRSULA; FERNÁNDEZ CASTILLEJO, SARA; Rubió, Laura; Macià, Alba; SOLÀ ALBERICH, ROSA MARIA
Keywords: anthocyanins mechanism-of-action healthcare
Abstract: Anthocyanins (ACNs) are promising health-enhancing phenolic compounds. We focus on ACN animal tissue bioavailability to provide an evidentiary link between tissue ACNs and their associated health properties. We performed a systematic review of electronic libraries; 279 results were retrieved, and 13 publications met inclusion criteria. Extracted information included animal model employed, administration route, doses, analysis method, and ACN concentration values in tissues. Total ACN concentrations were detected in mice kidney (2.17 × 105 pmol/g), liver (1.73 × 105 pmol/g), heart (3.6 × 103 pmol/g), and lung (1.16 × 105 pmol/g); and in pig brain (6.08 × 103 pmol/g). ACNs showed a predominance of parent ACNs in long-term experiments versus an ACN metabolite predominance in short-term experiments. ACNs detected in animal tissues, such as cyanidin-3-glucoside, suggest it may have an important role in human health. This information could be useful to determine proper ACN-intake biomarkers in biological samples in futures studies.
Research group: Unitat de Recerca de Lípids i Arteriosclerosi
Thematic Areas: Ciències de la salut Ciencias de la salud Health sciences
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 0021-8561
Author identifier: 0000-0002-6242-922X; 0000-0001-8884-9823; 0000-0002-8109-9713; 0000-0001-8973-2942; 0000-0001-6091-5606; 0000-0002-8359-235X
Record's date: 2019-03-21
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://pubs.acs.org/doi/10.1021/acs.jafc.8b04014
Funding program: plan; AppleCOR; AGL2016-76943-C2-2-R
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Article's DOI: 10.1021/acs.jafc.8b04014
Entity: Universitat Rovira i Virgili
Journal publication year: 2018
Publication Type: Article Artículo Article
Repositori URV