Author, as appears in the article.: Voltas, Nuria; Aparicio, Estefania; Arija, Victoria; Canals, Josefa
Department: Ciències Mèdiques Bàsiques; Psicologia
URV's Author/s: Aparicio Llopis, Estefania / Arija Val, Maria Victoria / Canals Sans, Josefa / Voltas Moreso, Núria
Keywords: Self report; Psychopathology; Promoter regions, genetic; Polymorphism, genetic; Phobic disorders; Personality inventory; Monoamine oxidase; Minisatellite repeats; Maoa-uvntr; Male; Longitudinal studies; Life change events; Humans; Genotype; Gender; Female; Depressive disorder; Anxiety disorders; Anxiety; Alleles; Adolescents; Adolescent; maoa-uvntr; gender; anxiety; adolescents
Abstract: The polymorphism upstream of the gene for monoamine oxidase A (MAOA-uVNTR) is reported to be an important enzyme involved in human physiology and behavior. With a sample of 228 early-adolescents from a community sample (143 girls) and adjusting for environmental variables, we examined the influence of MAOA-uVNTR alleles on the scores obtained in the Screen for Childhood Anxiety and Related Emotional Disorders and in the Child Symptom Inventory-4. Our results showed that girls with the high-activity MAOA allele had higher scores for generalized and total anxiety than their low-activity peers, whereas boys with the low-activity allele had higher social phobia scores than boys with the high-activity allele. Results for conduct disorder symptoms did not show a significant relationship between the MAOA alleles and the presence of these symptoms. Our findings support a possible association, depending on gender, between the MAOA-uVNTR polymorphism and psychopathological disorders such as anxiety, which affects high rates of children and adolescents.
Thematic Areas: Saúde coletiva; Psychology, clinical; Psychology; Psychiatry and mental health; Psychiatry; Psicología; Nutrição; Medicina ii; Medicina i; General medicine; Educação física; Clinical psychology; Ciencias sociales; Ciências biológicas ii
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: nuria.voltas@urv.cat; estefania.aparicio@urv.cat; josefa.canals@urv.cat; victoria.arija@urv.cat
Record's date: 2025-02-19
Paper version: info:eu-repo/semantics/submittedVersion
Link to the original source: https://www.sciencedirect.com/science/article/abs/pii/S0887618515000274?via%3Dihub
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Paper original source: Journal Of Anxiety Disorders. 31 65-72
APA: Voltas, Nuria; Aparicio, Estefania; Arija, Victoria; Canals, Josefa (2015). Association study of monoamine oxidase-A gene promoter polymorphism (MAOA-uVNTR) with self-reported anxiety and other psychopathological symptoms in a community sample of early adolescents. Journal Of Anxiety Disorders, 31(), 65-72. DOI: 10.1016/j.janxdis.2015.02.004
Article's DOI: 10.1016/j.janxdis.2015.02.004
Entity: Universitat Rovira i Virgili
Journal publication year: 2015
Publication Type: Journal Publications
Repositori URV