Author, as appears in the article.: Siqueira J., Sutton D., Gené J., García D., Wiederhold N., Peterson S., Guarro J.
Department: Ciències Mèdiques Bàsiques
URV's Author/s: García Sánchez, Dania / Gené Díaz, Josepa / Guarro Artigas, Josep / ZEN SIQUEIRA, JOAO PAULO
Keywords: Taxonomy Phenotypic identification Molecular phylogeny Molecular identification Clinical isolates Circumdati section Aspergillus section circumdati Aspergillus Antifungal susceptibility
Abstract: A multilocus phylogenetic study was carried out to assess species identity of a set of 34 clinical isolates from Aspergillus section Circumdati from the USA, and to determine their in vitro antifungal susceptibility against eight antifungal drugs. The genetic markers used were ITS, BenA, CaM and RPB2, and the drugs tested were amphotericin B, itraconazole, posaconazole, voriconazole, anidulafungin, caspofungin, micafungin, and terbinafine. The most common species sampled was A. westerdijkiae (29.4%), followed by a novel species, which was described here as A. pseudosclerotiorum (23.5%). Other species identified were A. sclerotiorum (17.6%), A. ochraceus (8.8%), A. subramanianii (8.8%), and A. insulicola and A. ochraceopetaliformis with two isolates (5.9%) each. The drugs that showed the most potent activity were caspofungin, micafungin, and terbinafine, while amphotericin B showed the least activity. Copyright 2017 American Society for Microbiology.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Odontología Microbiology (medical) Microbiology Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Farmacia Ensino Engenharias ii Enfermagem Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciência de alimentos Ciência da computação Biotecnología Biodiversidade
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 00951137
Author's mail: dania.garcias@urv.cat josepa.gene@urv.cat
Author identifier: 0000-0003-2397-1646 0000-0001-6195-9299
Record's date: 2024-09-07
Papper version: info:eu-repo/semantics/acceptedVersion
Link to the original source: https://jcm.asm.org/content/55/3/947
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Journal Of Clinical Microbiology. 55 (3): 947-958
APA: Siqueira J., Sutton D., Gené J., García D., Wiederhold N., Peterson S., Guarro J. (2017). Multilocus phylogeny and antifungal susceptibility of Aspergillus section Circumdati from clinical samples and description of A. pseudosclerotiorum sp. nov.. Journal Of Clinical Microbiology, 55(3), 947-958. DOI: 10.1128/JCM.02012-16
Article's DOI: 10.1128/JCM.02012-16
Entity: Universitat Rovira i Virgili
Journal publication year: 2017
Publication Type: Journal Publications
Repositori URV