Articles producció científica> Química Analítica i Química Orgànica

Metal-free and VOC-free O-glycosylation in supercritical CO2

  • Identification data

    Identifier: imarina:5131437
    Authors:
    Cardona ABoutureira OCastillón SDíaz YMatheu M
    Abstract:
    Supercritical carbon dioxide (scCO2) is a suitable medium to perform transition metal-free glycosylation reactions in the absence of volatile organic solvents (VOCs) using glycosyl halides as glycosyl donors. The methodology described here can be applied for obtaining O-glycosides in a totally green reaction, as well as orthoesters, depending on the reaction conditions. The process is much more sensitive to temperature changes than to pressure modification, with glycosyl chlorides requiring higher temperatures to be activated than glycosyl bromides. Pivaloyl groups act as good CO2-philic units and are shown to be the best choice to obtain good stereoselectivities. The relevance of the fluid nature and supercritical conditions was also evidenced.
  • Others:

    Author, as appears in the article.: Cardona A; Boutureira O; Castillón S; Díaz Y; Matheu M
    Department: Química Analítica i Química Orgànica
    URV's Author/s: Boutureira Martín, Omar / Castillón Miranda, Sergio / Díaz Giménez, María Yolanda / Matheu Malpartida, María Isabel
    Keywords: Clean water and sanitation
    Abstract: Supercritical carbon dioxide (scCO2) is a suitable medium to perform transition metal-free glycosylation reactions in the absence of volatile organic solvents (VOCs) using glycosyl halides as glycosyl donors. The methodology described here can be applied for obtaining O-glycosides in a totally green reaction, as well as orthoesters, depending on the reaction conditions. The process is much more sensitive to temperature changes than to pressure modification, with glycosyl chlorides requiring higher temperatures to be activated than glycosyl bromides. Pivaloyl groups act as good CO2-philic units and are shown to be the best choice to obtain good stereoselectivities. The relevance of the fluid nature and supercritical conditions was also evidenced.
    Thematic Areas: Química Pollution Medicina veterinaria Medicina ii Materiais Interdisciplinar Green & sustainable science & technology Farmacia Environmental chemistry Engenharias iv Engenharias iii Engenharias ii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Chemistry, multidisciplinary Chemistry Biotecnología Astronomia / física
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: omar.boutureira@urv.cat yolanda.diaz@urv.cat maribel.matheu@urv.cat sergio.castillon@urv.cat
    Author identifier: 0000-0002-0768-8309 0000-0001-5567-8108 0000-0001-5216-9260 0000-0002-0690-7549
    Record's date: 2024-11-16
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://pubs.rsc.org/en/content/articlelanding/2017/gc/c7gc00722a#!divAbstract
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Green Chemistry. 19 (11): 2687-2694
    APA: Cardona A; Boutureira O; Castillón S; Díaz Y; Matheu M (2017). Metal-free and VOC-free O-glycosylation in supercritical CO2. Green Chemistry, 19(11), 2687-2694. DOI: 10.1039/c7gc00722a
    Article's DOI: 10.1039/c7gc00722a
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2017
    Publication Type: Journal Publications
  • Keywords:

    Chemistry,Chemistry, Multidisciplinary,Environmental Chemistry,Green & Sustainable Science & Technology,Pollution
    Clean water and sanitation
    Química
    Pollution
    Medicina veterinaria
    Medicina ii
    Materiais
    Interdisciplinar
    Green & sustainable science & technology
    Farmacia
    Environmental chemistry
    Engenharias iv
    Engenharias iii
    Engenharias ii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Ciência de alimentos
    Chemistry, multidisciplinary
    Chemistry
    Biotecnología
    Astronomia / física
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