Articles producció científica> Medicina i Cirurgia

The use of inulin-type fructans improves stool consistency in constipated children. A randomised clinical trial: pilot study

  • Identification data

    Identifier: imarina:5131476
    Authors:
    Closa-Monasterolo, RicardoFerre, NataliaCastillejo-DeVillasante, GemmaLuque, VeronicaGispert-Llaurado, MarionaZaragoza-Jordana, MartaTheis, StephanEscribano, Joaquin
    Abstract:
    Constipation is a common disorder in children.The objective of this study is to assess the beneficial effects of a daily supplementation with Orafti® inulin-type fructans in 2-5 year old constipated children.Double-blind, randomised, placebo-controlled parallel group trial where constipated children received two doses of 2?g Orafti® inulin-type fructans (OF:IN) or placebo (maltodextrin) for 6 weeks. Primary outcome was stool consistency. Secondary outcomes were stool frequency and gastrointestinal symptoms.Twenty-two children were included, 17 completed the study protocol (nine and eight for the control and the OF:IN group, respectively). Results showed that Orafti® inulin-type fructans supplemented children had softer stools (p?=?.003). The longitudinal analysis showed no significant changes in controls, whereas supplemented children increased their stool consistency from 2.2 to 2.6 on the modified Bristol scale for children (five items instead of seven) (p?=?.040).Prebiotic inulin-type fructans supplementation improves stool consistency in constipated 2-5-year old children. Clinicaltrials.gov, with number NCT02863848.
  • Others:

    Author, as appears in the article.: Closa-Monasterolo, Ricardo; Ferre, Natalia; Castillejo-DeVillasante, Gemma; Luque, Veronica; Gispert-Llaurado, Mariona; Zaragoza-Jordana, Marta; Theis, Stephan; Escribano, Joaquin;
    Department: Medicina i Cirurgia
    URV's Author/s: Closa Monasterolo, Ricardo / Escribano Subías, Joaquín / Ferre Pallas, Natalia / Gispert Llauradó, Mariona / Luque Moreno, Verònica
    Keywords: Term infants Stool consistency Prebiotics Oligofructose Non-pharmacological treatment Inulin Infant formula Health Epidemiology Double-blind Dietary fiber intake Constipation Children Childhood constipation Adulthood prebiotics non-pharmacological treatment inulin constipation children
    Abstract: Constipation is a common disorder in children.The objective of this study is to assess the beneficial effects of a daily supplementation with Orafti® inulin-type fructans in 2-5 year old constipated children.Double-blind, randomised, placebo-controlled parallel group trial where constipated children received two doses of 2?g Orafti® inulin-type fructans (OF:IN) or placebo (maltodextrin) for 6 weeks. Primary outcome was stool consistency. Secondary outcomes were stool frequency and gastrointestinal symptoms.Twenty-two children were included, 17 completed the study protocol (nine and eight for the control and the OF:IN group, respectively). Results showed that Orafti® inulin-type fructans supplemented children had softer stools (p?=?.003). The longitudinal analysis showed no significant changes in controls, whereas supplemented children increased their stool consistency from 2.2 to 2.6 on the modified Bristol scale for children (five items instead of seven) (p?=?.040).Prebiotic inulin-type fructans supplementation improves stool consistency in constipated 2-5-year old children. Clinicaltrials.gov, with number NCT02863848.
    Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Odontología Nutrition & dietetics Nutrição Medicina veterinaria Medicina ii Medicina i Interdisciplinar General medicine Food science & technology Food science Farmacia Engenharias ii Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología Biodiversidade
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 09637486
    Author's mail: veronica.luque@urv.cat mariona.gispert@urv.cat mariona.gispert@urv.cat ricardo.closa@urv.cat natalia.ferre@urv.cat joaquin.escribano@urv.cat
    Author identifier: 0000-0003-2615-8175 0000-0002-9963-4163 0000-0002-2838-1525 0000-0002-5041-459X
    Record's date: 2024-09-07
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.tandfonline.com/doi/full/10.1080/09637486.2016.1263605
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: International Journal Of Food Sciences And Nutrition. 68 (5): 587-594
    APA: Closa-Monasterolo, Ricardo; Ferre, Natalia; Castillejo-DeVillasante, Gemma; Luque, Veronica; Gispert-Llaurado, Mariona; Zaragoza-Jordana, Marta; Theis (2017). The use of inulin-type fructans improves stool consistency in constipated children. A randomised clinical trial: pilot study. International Journal Of Food Sciences And Nutrition, 68(5), 587-594. DOI: 10.1080/09637486.2016.1263605
    Article's DOI: 10.1080/09637486.2016.1263605
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2017
    Publication Type: Journal Publications
  • Keywords:

    Food Science,Food Science & Technology,Nutrition & Dietetics
    Term infants
    Stool consistency
    Prebiotics
    Oligofructose
    Non-pharmacological treatment
    Inulin
    Infant formula
    Health
    Epidemiology
    Double-blind
    Dietary fiber intake
    Constipation
    Children
    Childhood constipation
    Adulthood
    prebiotics
    non-pharmacological treatment
    inulin
    constipation
    children
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Química
    Odontología
    Nutrition & dietetics
    Nutrição
    Medicina veterinaria
    Medicina ii
    Medicina i
    Interdisciplinar
    General medicine
    Food science & technology
    Food science
    Farmacia
    Engenharias ii
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Ciência de alimentos
    Biotecnología
    Biodiversidade
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