Author, as appears in the article.: Gómez-Canela C, Pueyo V, Barata C, Lacorte S, Marcé RM
Department: Química Analítica i Química Orgànica
URV's Author/s: Marcé Recasens, Rosa Maria
Keywords: Rivers Risk assessment Prioritization Pharmaceuticals Pecs risk assessment prioritization pharmaceuticals pecs
Abstract: The main objective of the present study is to prioritize those pharmaceuticals that have higher chances to be detected in water due to incomplete removal in Wastewater Treatment Plants (WWTPs). To do so, the total consumption of pharmaceuticals in Catalonia (NE Spain) were compiled to calculate the predicted environmental concentrations (PECs) in wastewater effluents and in river water. PECs were estimated using publicly available consumption data in the period of 2013-2016 for a suite of 165 compounds. The selected compounds were based on generic pharmaceuticals with emphasis on drugs consumed by people aged 65 or over as they represent the age group with the highest consumption of pharmaceuticals. The mean total consumption of pharmaceuticals in the period studied was of 623?±?3?t per year. Paracetamol, metformin and ibuprofen were the most administered drugs although the highest PEC values corresponded to metformin, amoxicillin and metamizole. Finally, predicted environmental levels together with acute and chronic toxicological data allowed estimating the risks of these compounds. Amoxicillin is expected to pose adverse effects for cyanobacteria, whereas metformin and ibuprofen pose a small potential for adverse effects to invertebrates and fish, respectively.Copyright © 2019 Elsevier B.V. All rights reserved.
Thematic Areas: Zootecnia / recursos pesqueiros Waste management and disposal Saúde coletiva Química Pollution Odontología Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Interdisciplinar Historia Geografía Geociências Farmacia Environmental sciences Environmental engineering Environmental chemistry Ensino Engenharias iii Engenharias ii Engenharias i Enfermagem Direito Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Biotecnología Biodiversidade Astronomia / física
ISSN: 00489697
Author's mail: rosamaria.marce@urv.cat
Author identifier: 0000-0002-5667-2899
Last page: 65
Record's date: 2023-02-22
Journal volume: 666
Papper version: info:eu-repo/semantics/acceptedVersion
Link to the original source: https://www.sciencedirect.com/science/article/pii/S0048969719305583
Papper original source: Science Of The Total Environment. 666 57-67
APA: Gómez-Canela C, Pueyo V, Barata C, Lacorte S, Marcé RM (2019). Development of Predicted Environmental Concentrations to prioritize the occurrence of pharmaceuticals in rivers from Catalonia. Science Of The Total Environment, 666(), 57-67. DOI: 10.1016/j.scitotenv.2019.02.078
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Article's DOI: 10.1016/j.scitotenv.2019.02.078
Entity: Universitat Rovira i Virgili
Journal publication year: 2019
First page: 57
Publication Type: Journal Publications
Repositori URV