Articles producció científica> Química Analítica i Química Orgànica

Synthesis of Fluorosugar Reagents for the Construction of Well-Defined Fluoroglycoproteins

  • Identification data

    Identifier: imarina:6024486
    Handle: https://hdl.handle.net/20.500.11797/imarina6024486
    Authors:
    Salvado, MiriamAmgarten, BeatriceCastillon, SergioBernardes, Goncalo J LBernardes, Goncalo J LBoutureira, Omar
    Abstract:
    2-Deoxy-2-fluoroglycosyl iodides are privileged glycosyl donors for the stereoselective preparation of 1-Nu-beta-fluorosugars, which are useful reagents for chemical site-selective protein glycosylation. Ready access to such beta-fluorosugars enables the mild and efficient construction of well-defined fluoroglycoproteins.

  • Others:

    Author, as appears in the article.: Salvado, Miriam; Amgarten, Beatrice; Castillon, Sergio; Bernardes, Goncalo J L; Bernardes, Goncalo J L; Boutureira, Omar
    Department: Química Analítica i Química Orgànica
    URV's Author/s: Boutureira Martín, Omar / Castillón Miranda, Sergio / Salvadó Artells, Marçal
    Keywords: Proteins Positron-emission-tomography Phase-transfer catalysis Pet Peptides Nmr-spectra Glycosyl iodides Glycoprotein Glycopeptides Bioconjugation
    Abstract: 2-Deoxy-2-fluoroglycosyl iodides are privileged glycosyl donors for the stereoselective preparation of 1-Nu-beta-fluorosugars, which are useful reagents for chemical site-selective protein glycosylation. Ready access to such beta-fluorosugars enables the mild and efficient construction of well-defined fluoroglycoproteins.
    Thematic Areas: Química Physical and theoretical chemistry Organic chemistry Medicina ii Medicina i Materiais Interdisciplinar General medicine Farmacia Ciências biológicas ii Ciências biológicas i Ciências agrárias i Chemistry, organic Biotecnología Biodiversidade Biochemistry
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: omar.boutureira@urv.cat m.salvado@urv.cat sergio.castillon@urv.cat
    Author identifier: 0000-0002-0768-8309 0000-0002-9399-6649 0000-0002-0690-7549
    Record's date: 2024-09-28
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://pubs.acs.org/doi/10.1021/acs.orglett.5b01259
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Organic Letters. 17 (11): 2836-2839
    APA: Salvado, Miriam; Amgarten, Beatrice; Castillon, Sergio; Bernardes, Goncalo J L; Bernardes, Goncalo J L; Boutureira, Omar (2015). Synthesis of Fluorosugar Reagents for the Construction of Well-Defined Fluoroglycoproteins. Organic Letters, 17(11), 2836-2839. DOI: 10.1021/acs.orglett.5b01259
    Article's DOI: 10.1021/acs.orglett.5b01259
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2015
    Publication Type: Journal Publications

  • Keywords:

    Biochemistry,Chemistry, Organic,Organic Chemistry,Physical and Theoretical Chemistry
    Proteins
    Positron-emission-tomography
    Phase-transfer catalysis
    Pet
    Peptides
    Nmr-spectra
    Glycosyl iodides
    Glycoprotein
    Glycopeptides
    Bioconjugation
    Química
    Physical and theoretical chemistry
    Organic chemistry
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    General medicine
    Farmacia
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Chemistry, organic
    Biotecnología
    Biodiversidade
    Biochemistry

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