Incidence of diabetes mellitus in Spain as results of the nation-wide cohort di@bet.es study

Identifier:  imarina:6108799

Handle: https://hdl.handle.net/20.500.11797/imarina6108799

Authors:  Rojo-Martinez, G; Valdes, S; Soriguer, F; Vendrell, J; Urrutia, I; Perez, V; Ortega, E; Ocon, P; Montanya, E; Menendez, E; Lago-Sampedro, A; Gonzalez-Frutos, T; Gomis, R; Goday, A; Garcia-Serrano, S; Garcia-Escobar, E; Galan-Garcia, J L; Castell, C; Badia-Guillen, R; Aguilera-Venegas, G; Girbes, J; Gaztambide, S; Franch-Nadal, J; Delgado, E; Chaves, F J; Castano, L; Calle-Pascual, A

Abstract:
© 2020, The Author(s). Our aim was to determine the incidence of type 2 diabetes mellitus in a nation-wide population based cohort from Spain (di@bet.es study). The target was the Spanish population. In total 5072 people older than 18 years,were randomly selected from all over Spain). Socio-demographic and clinical data, survey on habits (physical activity and food consumption) and weight, height, waist, hip and blood pressure were recorder. A fasting blood draw and an oral glucose tolerance test were performed. Determinations of serum glucose were made. In the follow-up the same variables were collected and HbA1c was determined. A total of 2408 subjects participated in the follow-up. In total, 154 people developed diabetes (6.4% cumulative incidence in 7.5 years of follow-up). The incidence of diabetes adjusted for the structure of age and sex of the Spanish population was 11.6 cases/1000 person-years (IC95% = 11.1–12.1). The incidence of known diabetes was 3.7 cases/1000 person-years (IC95% = 2.8–4.6). The main risk factors for developing diabetes were the presence of prediabetes in cross-sectional study, age, male sex, obesity, central obesity, increase in weight, and family history of diabetes. This work provides data about population-based incidence rates of diabetes and associated risk factors in a nation-wide cohort of Spanish population.