The Assisi Think Tank Meeting Survey of post-mastectomy radiation therapy in ductal carcinoma in situ: Suggestions for routine practice

Identifier:  imarina:6127495

Handle: https://hdl.handle.net/20.500.11797/imarina6127495

Authors:  Montero-Luis, A; Aristei, C; Meattini, I; Arenas, M; Boersma, L; Bourgier, C; Coles, C; Cutuli, B; Falcinelli, L; Kaidar-Person, O; Leonardi, M C; Offersen, B; Marazzi, F; Rivera, S; Tagliaferri, L; Tombolini, V; Vidali, C; Valentini, V; Poortmans, P

Abstract:
© 2019 Elsevier B.V. Background: Risk factors for local recurrence after mastectomy in ductal carcinoma in situ (DCIS) emerged as a grey area during the second “Assisi Think Tank Meeting” (ATTM) on Breast Cancer. Aim: To review practice patterns of post-mastectomy radiation therapy (PMRT) in DCIS, identify risk factors for recurrence and select suitable candidates for PMRT. Methods: A questionnaire concerning DCIS management, focusing on PMRT, was distributed online via SurveyMonkey. Results: 142 responses were received from 15 countries. The majority worked in academic institutions, had 5–20 years work-experience and irradiated <5 DCIS patients/year. PMRT was more given if: surgical margins <1 mm, high-grade, multicentricity, young age, tumour size >5 cm, skin- or nipple- sparing mastectomy. Moderate hypofractionation was the most common schedule, except after immediate breast reconstruction (57% conventional fractionation). Conclusions: The present survey highlighted risk factors for PMRT administration, which should be further evaluated.