Author, as appears in the article.: Yong L; Wiederhold N; Sutton D; Sandoval-Denis M; Lindner J; Fan H; Sanders C; Guarro J
Department: Ciències Mèdiques Bàsiques
URV's Author/s: Guarro Artigas, Josep / SANDOVAL DENIS, MARCELO PATRICIO
Keywords: Wangiella-dermatitidis United-states Subcutaneous pheohyphomycosis Spinifera Spectrum Primer sets Infections Humans Cystic-fibrosis Cryptococcal meningitis
Abstract: © 2015 American Society for Microbiology. All Rights Reserved. Exophiala species are capable of causing cutaneous and subcutaneous infections in immunocompromised patients. An Exophiala isolate was cultured from a biopsy specimen of a lesion on the forearm of a patient with myasthenia gravis. The patient also had lesions on the palm and distal aspects of the hand, which were successfully treated with a long-term course of itraconazole. A detailed morphological and molecular characterization of the isolate was undertaken. Phylogenetic analysis of the internal transcribed spacer region and portions of the β-tubulin and translation elongation factor 1-alpha genes indicated that the isolate was a novel species closely related to but genetically distinct from species within the Exophiala spinifera clade; the name Exophiala polymorpha sp. nov. is proposed. Morphologically, E. polymorpha most closely resembles E. xenobiotica but it differs in possessing phialides bearing prominent, wide collarettes, and it does not produce chlamydospores.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Odontología Microbiology (medical) Microbiology Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Farmacia Ensino Engenharias ii Enfermagem Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciência de alimentos Ciência da computação Biotecnología Biodiversidade
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 00951137
Author's mail: josep.guarro@urv.cat
Author identifier: 0000-0002-7839-7568
Record's date: 2024-07-20
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://journals.asm.org/doi/10.1128/jcm.00622-15
Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Journal Of Clinical Microbiology. 53 (9): 2816-2822
APA: Yong L; Wiederhold N; Sutton D; Sandoval-Denis M; Lindner J; Fan H; Sanders C; Guarro J (2015). Morphological and molecular characterization of Exophiala polymorpha sp. nov. isolated from sporotrichoid lymphocutaneous lesions in a patient with myasthenia gravis. Journal Of Clinical Microbiology, 53(9), 2816-2822. DOI: 10.1128/JCM.00622-15
Article's DOI: 10.1128/JCM.00622-15
Entity: Universitat Rovira i Virgili
Journal publication year: 2015
Publication Type: Journal Publications
Repositori URV