Author, as appears in the article.: Romeu, Marta; Rubio, Laura; Sanchez-Martos, Vanessa; Castaner, Olga; de la Torre, Rafael; Valls, Rosa M; Ras, Rosa; Pedret, Anna; Catalan, Ursula; Lopez de las Hazas, Maria del Carmen; Motilva, Maria J; Fito, Montserrat; Sola, Rosa; Giralt, Montserrat
Department: Ciències Mèdiques Bàsiques; Medicina i Cirurgia
URV's Author/s: Catalán Santos, Úrsula / Giralt Batista, Montserrat / Giralt Esteve, Mireia / Pedret Figuerola, Anna / Ras Mallorquí, Maria Rosa / Romeu Ferran, Marta / ROMEU FIGUEROLA, MARIA CARMEN / Sánchez Martos, Vanessa / Solà Alberich, Rosa Maria / Valls Zamora, Rosa Maria
Keywords: Virgin olive oil; Thyme phenols; Phenol enrichment; Oxidative stress; Hyperlipidemia; Enzymatic antioxidants; thyme phenols; phenol enrichment; oxidative stress; hyperlipidemia; enzymatic antioxidants
Abstract: © 2016 American Chemical Society. The effects of virgin olive oil (VOO) enriched with its own phenolic compounds (PC) and/or thyme PC on the protection against oxidative DNA damage and antioxidant endogenous enzymatic system (AEES) were estimated in 33 hyperlipidemic subjects after the consumption of VOO, VOO enriched with its own PC (FVOO), or VOO complemented with thyme PC (FVOOT). Compared to pre-intervention, 8-hydroxy-2′-deoxyguanosine (a marker for DNA damage) decreased in the FVOO intervention and to a greater extent in the FVOOT with a parallel significant increase in olive and thyme phenolic metabolites. Superoxide dismutase (AEES enzyme) significantly increased in the FVOO intervention and to a greater extent in the FVOOT with a parallel significant increase in thyme phenolic metabolites. When all three oils were compared, FVOOT appeared to have the greatest effect in protecting against oxidative DNA damage and improving AEES. The sustained intake of a FVOOT improves DNA protection against oxidation and AEES probably due to a greater bioavailability of thyme PC in hyperlipidemic subjects.
Thematic Areas: Zootecnia / recursos pesqueiros; Saúde coletiva; Química; Planejamento urbano e regional / demografia; Odontología; Nutrição; Medicina veterinaria; Medicina ii; Medicina i; Materiais; Interdisciplinar; General medicine; General chemistry; General agricultural and biological sciences; Food science & technology; Farmacia; Ensino; Engenharias iv; Engenharias iii; Engenharias ii; Educação; Ciências biológicas iii; Ciências biológicas ii; Ciências biológicas i; Ciências ambientais; Ciências agrárias i; Ciência de alimentos; Ciência da computação; Chemistry, applied; Chemistry (miscellaneous); Chemistry (all); Biotecnología; Biodiversidade; Astronomia / física; Agriculture, multidisciplinary; Agriculture; Agricultural and biological sciences (miscellaneous); Agricultural and biological sciences (all)
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 00218561
Author's mail: ursula.catalan@urv.cat; anna.pedret@urv.cat; montse.giralt@urv.cat; vanessa.sanchez@urv.cat; vanessa.sanchez@urv.cat; rosamaria.valls@urv.cat; marta.romeu@urv.cat; rosa.sola@urv.cat
Record's date: 2025-01-28
Paper version: info:eu-repo/semantics/acceptedVersion
Link to the original source: https://pubs.acs.org/doi/10.1021/acs.jafc.5b04915
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Paper original source: Journal Of Agricultural And Food Chemistry. 64 (9): 1879-1888
APA: Romeu, Marta; Rubio, Laura; Sanchez-Martos, Vanessa; Castaner, Olga; de la Torre, Rafael; Valls, Rosa M; Ras, Rosa; Pedret, Anna; Catalan, Ursula; Lop (2016). Virgin Olive Oil Enriched with Its Own Phenols or Complemented with Thyme Phenols Improves DNA Protection against Oxidation and Antioxidant Enzyme Activity in Hyperlipidemic Subjects. Journal Of Agricultural And Food Chemistry, 64(9), 1879-1888. DOI: 10.1021/acs.jafc.5b04915
Article's DOI: 10.1021/acs.jafc.5b04915
Entity: Universitat Rovira i Virgili
Journal publication year: 2016
Publication Type: Journal Publications
Repositori URV